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Yibian
 Shen Yaozi 
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diseaseFamilial Intestinal Tumor Disease
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bubble_chart Overview

Polyps of varying sizes, ranging from ten to several hundred, are widely distributed in the intestines, particularly the large intestine. In severe cases, polyps can occur from the mouth all the way to the rectum and anal canal, often accompanied by other specific clinical symptoms. This disease is generally believed to be related to genetic factors and often has a family history. In cases with extensive lesions, apart from the common bleeding symptoms of polyps, malignant transformation can frequently occur. Therefore, timely surgical intervention is necessary, and those who cannot undergo surgery should undergo regular follow-ups to prevent complications. The disease is associated with genetic factors, with no significant gender difference. It typically manifests after the age of 20. The lesions are widespread, and if surgical treatment is deficient, malignant transformation may occur.

bubble_chart Clinical Manifestations

  1. Stool with mucus and bloody stool, increased frequency of bowel movements.
  2. Weight loss, lack of strength, anemia, and varying degrees of abdominal discomfort or abdominal pain.
  3. Or accompanied by soft bone tumors and other extraintestinal tumors.
  4. Polyps are mainly located in the large intestine.
  5. Digital rectal examination can detect polyps.

bubble_chart Diagnosis

  1. There is a positive family history.
  2. Hematochezia, increased frequency of bowel movements, and stools with more mucus are common. Symptoms such as weight loss, lack of strength, and anemia may occur, along with varying degrees of abdominal discomfort or abdominal pain.
  3. Digital rectal examination may reveal polyps of varying sizes.
  4. Colonoscopy shows polyps scattered throughout the rectum and colon, and a biopsy can confirm the diagnosis.
  5. Barium enema reveals multiple filling defects.

bubble_chart Treatment Measures

  1. For cases with simple colonic or intestinal tumors as the main manifestation, total colectomy can be performed, along with ileostomy or ileal pouch-anal anastomosis. Regular follow-up is required to monitor the condition of the residual rectal mucosa.
  2. Total colectomy with rectal mucosal stripping, ileal pouch formation, and anal anastomosis within the rectal sheath.
  3. For patients with polyps throughout the entire digestive tract that cannot be completely cured, partial intestinal resection may be performed when complications such as intussusception or massive bleeding occur.
  4. Symptomatic and supportive therapy.
  5. Chinese medicine, including oral administration, external treatment, and enema.

bubble_chart Related Drugs

Principles of Medication

  1. For those who cannot undergo surgery, gentamicin, metronidazole, general hemostatic medicinal substances, vitamins, and Chinese medicinals may be administered orally or via enema.
  2. For localized large intestine polyps, surgical resection can be performed.
  3. If complications arise or the polyp becomes malignant, resection of the affected intestinal segment is required, along with treatments such as "A," "B," "C" items, fluid infusion, antibiotics, hemostatic medicinal substances, vitamins, and other medications.
    1. Aminomethylbenzoic Acid A, Metronidazole A, Gentamicin Sulfate B, Potassium Chloride
    2. Glucose B, Vitamin C
    3. Human Albumin C, Compound Amino Acids.

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