This product is the nearly mature fruit of the deciduous shrub or small tree plant Evodia Fruit (Euodia ruticarpa (A. Juss.) Benth.), Stone Tiger (E. ruticarpa (A. Juss.) Benth. var. officinalis (Dode) Huang), or Sparse-haired Evodia Fruit (E. ruticarpa (A. Juss.) Benth. var. bodinieri (Dode) Huang). It is mainly produced in Guizhou, Guangxi, Hunan, Zhejiang, Sichuan, and other regions. The fruits are harvested from August to November before they split open, then dried in the sun or at low temperatures. They can be used raw or processed.

bubble_chart Properties and Meridians

Acrid and bitter, hot. slightly toxic. Act on liver, spleen, stomach and kidney meridians.

bubble_chart Efficacy

Dispersing cold to alleviate pain, warming the middle to stop vomiting, and assisting yang to halt diarrhea.

bubble_chart Indications

1. Used for various pain syndromes due to cold stagnation in the liver meridian. This herb is pungent and dispersing, bitter and draining, hot in nature and cold-dispelling. It not only disperses cold evil from the liver meridian but also relieves liver qi stagnation, making it an essential herb for treating pain due to liver cold qi stagnation. For cold abdominal colic and abdominal pain, it is often combined with Fennel, Chinaberry Fruit, Aucklandia Root, and other medicinal combinations, such as Qi-Guiding Decoction from "Yi Fang Jian Yi." For Jueyin headache, it is often used with Ginseng, Fresh Ginger Rhizome, etc., such as Evodia Decoction. For dysmenorrhea due to deficiency and cold in the Chong and Ren meridians with static blood obstruction, it can be used with Cinnamon Twig, Chinese Angelica, Sichuan Lovage Rhizome, etc., such as Meridian-Warming Decoction. For cold-dampness beriberi with swelling and pain, or upward rushing into the abdomen, it is often used with Floweringqince Fruit, cultivated purple perilla leaf, Areca Seed, etc., such as Cock Crow Powder.
2. Used for stomach cold vomiting syndrome. This herb has the functions of warming the middle and dissipating cold, downbearing counterflow to stop vomiting. For middle energizer deficiency and cold with epigastric cold pain and vomiting with acid regurgitation, it is often used with Ginseng, Fresh Ginger Rhizome, etc., such as Evodia Decoction. For vomiting due to external cold invasion and stomach disharmony, it can be used with Pineilia, Fresh Ginger Rhizome, etc.
3. Used for deficiency cold diarrhea syndrome. This herb can warm the spleen and benefit the kidneys, assist yang and stop diarrhea, making it a common herb for treating spleen-kidney yang deficiency with diarrhea before dawn. It is often used with Psoralea, Nutmeg, Schisandra Fruit, etc., such as Four Miracle Pill. Additionally, applying this herb as a powder mixed with vinegar to the sole of the foot (Yongquan acupoint) can treat aphtha, and it is also used in modern clinical practice to treat hypertension.

bubble_chart Documentation

1. Benjing: "Main warming the middle and lowering qi, relieving pain, cough and counterflow cold and heat, eliminating dampness, blood impediment, expelling wind evil, opening striae and interstice."
2. Bencao Gangmu: "Opening depression and transforming stagnation, treating acid swallow, Jueyin phlegm-drool headache, yin toxin abdominal pain, hernia blood dysentery, throat and tongue aphtha."

bubble_chart Usage and Dosage

Decoct and take 1.5-6g. Apply an appropriate amount externally.

bubble_chart Cautions and Contraindications

This product is pungent, hot, and drying, and can easily deplete qi and stir up fire, so it should not be used excessively or for prolonged periods.

bubble_chart Modern Pharmacology

This product contains volatile oil. The main components in the oil are Evodia Fruit alkene, Basil Herb alkene, Evodia Fruit lactone, Evodia Fruit lactone alcohol, etc. In addition, it also contains Evodia Fruit acid, Evodia Fruit bitterin, Evodia Fruit alkaloid, Evodia Fruit subalkaloid, and other alkaloids.

• This product has analgesic effects.
• It can raise body temperature, and in large doses, it can excite the central nervous system and cause visual disturbances and illusions.
• When its decoction is administered to dogs via gastric lavage, it has a significant hypotensive effect. However, when combined with Liquorice Root, the hypotensive effect disappears. The hypotensive effect is mainly due to the dilation of peripheral blood vessels and is related to histamine release.
• The effect of its decoction on the small intestine activity of rabbits is excitatory at low concentrations and inhibitory at high concentrations.
• This product can inhibit platelet aggregation and the formation of platelet thrombi and fibrin thrombi.
• The decoction of this product, Evodia Fruit subalkaloid, and dehydro Evodia Fruit alkaloid have excitatory effects on the isolated and in situ uterus of rabbits.