formula | Four Miracle Pill Si Shen Wan |
source | Summary of Internal Medicine, Volume 2 |
Nutmeg (raw) 60 gm, Psoralea (stir-fried) 120 gm, Schisandra 60 gm, Evodia 120 gm.
bubble_chart Preparation and Dosage
Grind the above ingredients into powder, add 50 red dates and 120 grams of fresh ginger, cut and crushed, boil with water until the dates are cooked, remove the ginger, take the date flesh and mix with the medicine to form pills as big as a phoenix tree seed. Take 50 to 70 pills before meals.
Warm the kidneys and spleen, astringe and stop diarrhea.
Spleen and kidney deficiency with cold, loose stools, lack of appetite, or indigestion, or abdominal pain, mental fatigue and lack of strength, pale tongue with thin white coating, deep and slow weak pulse. Commonly used for chronic diarrhea, intestinal adhesion, and other conditions characterized by spleen and kidney deficiency with cold, such as chronic diarrhea or early morning diarrhea.
bubble_chart Formula Principles
This formula is a combination of the Er Shen Wan and Schisandra Fruit Powder. In the formula, Psoralea warms the kidneys and spleen, serving as the sovereign; Evodia Fruit warms the middle and dissipates cold, while Nutmeg warms the spleen and stomach, astringes the intestines, and checks diarrhea, serving as the ministers. Together, they treat both the spleen and kidneys, ensuring that the life gate fire is sufficient, allowing the spleen yang to function properly, and enhancing the warming yang and astringing intestines effects. Schisandra Fruit, with its sour and astringent properties, works in conjunction with Fresh Ginger Rhizome to warm the stomach and dissipate cold, and Chinese Date to tonify the spleen and nourish the stomach, serving as the assistants and messengers.
bubble_chart Modern ApplicationEffects on the motility of isolated small intestine. "Research on Chinese Patent Drugs" 1981(9):31. The Four Miracle Pill and its components, the Two Divine Pills and Schisandra Fruit Powder, as well as the single herbs Schisandra Fruit and Evodia Fruit, significantly inhibit the spontaneous activity of isolated rabbit intestines and can counteract intestinal spasms induced by acetylcholine and barium chloride. A comparison of the intestinal inhibitory effects of the Four Miracle Pill and adrenaline indicates that the inhibitory effect of this formula is not mediated through α-receptors.