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Yibian
 Shen Yaozi 
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formulaMume Pill Wu Mei Wan
sourceShanghan Lun
smart_toy
bubble_chart Composition

300 pieces of dark plum, 84 grams of Asarum, 140 grams of dried ginger, 224 grams of Coptis, 56 grams of Angelica, 84 grams of Aconite (peeled, prepared), 56 grams of Sichuan pepper (sweated), 84 grams of cinnamon (peeled), 84 grams of ginseng, 84 grams of Phellodendron.

bubble_chart Preparation and Dosage

Grind and sieve the above 10 ingredients, mix them thoroughly. Soak the pitted dark plum in bitter wine overnight, then steam it with rice. Once the rice is cooked, mash it into a paste and mix it with the medicine until well combined. Place the mixture in a mortar, add honey, and pound it 2000 times to form pills as big as a phoenix tree seed. Take 10 pills before meals, three times a day, gradually increasing to 20 pills.

bubble_chart Efficacy

Warming viscera and quietening ascaris.

bubble_chart Indications

Gallbladder ascariasis is characterized by paroxysmal abdominal pain, restless vomiting that comes and goes, vomiting immediately after eating, even vomiting worms, cold reversal of hands and feet; or prolonged dysentery, regurgitation, and a deep, thin or wiry, tight pulse. It is now used for biliary ascariasis.

bubble_chart Formula Principles

The formula is used to treat gallbladder ascariasis, which is caused by stomach heat and intestinal cold, leading to restless movement of the ascarids. Ascarids become calm in the presence of sourness, subdued in the presence of pungency, and expelled in the presence of bitterness. Therefore, the formula heavily employs Smoked Plum, which is sour in taste, to quiet the ascarids. It is combined with Asarum, Dried Ginger, Cinnamon Twig, Aconite Lateral Root, and Pricklyash Peel, which are pungent and hot in nature, to warm the organs and expel the ascarids. Coptis Rhizome and Phelloendron Bark, which are bitter and cold, are used to clear heat and expel the ascarids. Additionally, Ginseng and Chinese Angelica are used to tonify and replenish qi and blood, addressing the deficiency of healthy qi. The entire formula works together to warm the viscera and quiet the ascarids, treating both cold and heat, and addressing both pathogenic factors and healthy qi.

bubble_chart Cautions and Contraindications

Avoid raw, cold, slippery, and foul-smelling foods while taking medication.

bubble_chart Modern Application

The effects of expelling bile and driving out ascaris, etc. "Chinese Patent Drug Research" 1986(3): 33-35. This formula can promote gallbladder contraction and bile expulsion, which is beneficial for gallbladder drainage, reducing or preventing biliary tract infections and the retention of ascaris eggs in the biliary tract, which can form the core of gallstones, thereby reducing the occurrence of gallstones. Increasing the dose of Smoked Plum enhances the effect more significantly, but using Smoked Plum alone is not as effective as the compound formula, indicating that the compound formula has a synergistic effect. Experiments also show that this formula anesthetizes ascaris, causing them to lose their ability to adhere to the intestinal wall, promotes an increase in bile secretion by the liver, lowers the pH value, significantly dilates the sphincter of Oddi, and has a strong broad-spectrum antibacterial effect, particularly against dysentery bacilli.

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