A positive tuberculin test result of ≥ "++" without identifiable specific subcutaneous node lesions is referred to as subcutaneous node infection.

bubble_chart Clinical Manifestations

1. Weak constitution is prone to respiratory infections.
2. None or presence of subcutaneous node poisoning symptoms (see primary pulmonary subcutaneous node).
3. Superficial lymph nodes show grade I enlargement with increased numbers.
4. A small number of children exhibit subcutaneous node hypersensitivity symptoms (see primary pulmonary subcutaneous node). The subcutaneous node tuberculin (OT or PPD) test results show redness, swelling, and induration ≥10mm, which can exclude reactions caused by BCG vaccination.

bubble_chart Auxiliary Examination

1. Blood picture: Older children may have grade I anemia.
2. ESR is not elevated.
3. Serum anti-subcutaneous node bacterial purified protein derivative─globulin (PPD-IgG) is positive.

bubble_chart Treatment Measures

1. INH 5～10mg/(kg·d), maximum dose not exceeding 300mg/d, administered in a single draught on an empty stomach in the morning, treatment course of 6 months, which can be extended to 9～12 months if necessary.
2. General therapy: same as primary pulmonary subcutaneous node.