Cerebral subcutaneous node tumor is a granulomatous lesion formed after infection of the central nervous system by subcutaneous node bacillus. It often occurs secondary to subcutaneous node in other parts of the body. After the liberation, nationwide mass prevention and treatment of subcutaneous node disease were carried out, and with the improvement of people's living standards, the incidence of subcutaneous node in China has been significantly reduced. Currently, the incidence of cerebral subcutaneous node tumor is

1. 4%, accounting for about 4% of intracranial space-occupying lesions. It can occur in any part of the intracranial cavity, with a higher incidence in the infratentorial region than the supratentorial region. It mostly occurs in children and adolescents, with no significant difference in incidence between males and females. Clinically, cerebral subcutaneous node tumors are divided into two types: 1. Systemic type: accompanied by active subcutaneous node in other organs, such as the lungs, lymph nodes, or even systemic foxtail millet-like subcutaneous node, often associated with subcutaneous node meningitis. The general condition is poor, and the prognosis is generally unfavorable. 2. Localized type: The main clinical manifestations are epileptic seizures and symptoms of intracranial hypertension, and the surgical treatment effect is relatively good.

bubble_chart Clinical Manifestations

1. Systemic type: (1) Symptoms such as hemoptysis, cough, fever, night sweating, emaciation, and subcutaneous nodules. (2) Accompanied by manifestations of bone and joint subcutaneous nodules, chronic abscesses in the chest wall and cervical lymph nodes, or tuberculous meningitis. (3) Signs of increased intracranial pressure and cerebellar dysfunction: patients exhibit headache, vomiting, papilledema, focal brain damage symptoms, nystagmus, and limb ataxia. 2. Localized type: (1) Symptoms include low-grade fever, night sweating, emaciation, accelerated erythrocyte sedimentation rate, and subcutaneous nodules. (2) Symptoms of intracranial hypertension and focal brain damage, presenting as headache, vomiting, papilledema, hemiplegia, aphasia, epileptic seizures, and cerebellar damage symptoms such as nystagmus and limb ataxia.

1. The medical history includes symptoms such as chronic weight loss, low-grade fever, night sweating, general malnutrition, hemoptysis, and cough, as well as manifestations like headache, vomiting, blurred vision, unilateral limb weakness, slurred speech, unsteady gait, and epileptic seizures. 2. Physical examination reveals changes in vision and visual fields, fundal edema, or hemiplegia, unilateral sensory disturbances, aphasia, and cerebellar signs. 3. Examination of other body parts shows subcutaneous nodules, such as chest subcutaneous nodules on X-ray or bone and joint subcutaneous nodules. 4. Increased erythrocyte sedimentation rate (ESR). 5. Lumbar puncture is generally feasible, often showing elevated pressure. Analysis of cerebrospinal fluid (CSF) reveals increased protein levels, elevated white blood cell counts (predominantly mononuclear cells), and decreased glucose levels. 6. Skull X-rays may show signs of increased intracranial pressure and occasionally calcification of subcutaneous nodular tumors. 7. Head CT scans and magnetic resonance imaging (MRI) can determine the size of the lesions.

bubble_chart Treatment Measures

1. Systemic type: Administer anti-subcutaneous node medication first. 2. Localized type: Surgically remove the intracranial lesion. 3. Use anti-subcutaneous node medication for 3-6 months, starting 1-2 weeks before surgery and continuing postoperatively.

Cerebral subcutaneous node tumor is an intracranial granuloma secondary to subcutaneous node disease in other parts of the body. Subcutaneous node disease, commonly known as "pulmonary tuberculosis," is primarily a respiratory pestilence-transmitted disease. Prevention is key in treatment, focusing on avoiding contact with pestilence sources. Vaccination after birth confers acquired immunity. Patients exhibiting subcutaneous node symptoms such as anemia, night sweating, weight loss, lack of strength, and low-grade fever should seek prompt medical diagnosis and treatment, self-isolate to prevent infection spread, and follow prescribed anti-subcutaneous node medication. For those with subcutaneous node disease accompanied by intracranial hypertension or brain damage symptoms, consultation with a specialist is advised. Diagnosis typically involves cranial CT scans or MRI. Systemic cases are treated first with anti-subcutaneous node therapy as prescribed, while localized cases primarily undergo surgical treatment, with a generally favorable prognosis.

1. Cure: After anti-subcutaneous node treatment and surgery, the source of the disease is eliminated. Local symptoms and signs disappear. 2. Improvement: After anti-subcutaneous node treatment, the source of the disease shrinks, and local symptoms and signs improve. 3. No cure: The source of the disease enlarges, and local symptoms and signs worsen.