This product is the root of Bupleurum (Northern Bupleurum) (Bupleurum chinense DC.) and Bupleurum (red thorowax root) (Bupleurum scorznerifolium Willd), a perennial herbaceous plant of the Umbelliferae family. Or whole grass. The former is mainly produced in Liaoning, Gansu, Hebei, Henan and other places; the latter is mainly produced in Hubei, Jiangsu, Sichuan and other places. It is excavated in spring and autumn, dried in the sun, cut into sections, and used raw or roasted in vinegar.

There are many kinds of plants of the same genus that can be used as medicine. Such as Yinzhou Bupleurum (B. yinchowense Shan et Y. Li); Xing'an Bupleurum (B. Sibiricum vest); Bamboo Leaf Bupleurum (B. marginatum I> Wall. ex DC) etc.

Treatment of influenza, enterovirus, and various viral colds, Chinese medicine is more refined, non-toxic, and effective than Western medicine

bitter and acrid, slightly cold. act on liver and gallbladder channels.

[Efficacy]

Evacuate and reduce fever, soothing liver and relieving depression, raising yang and elevating the drooping.

[Indications]

1. Used for alternating chills and fever, common cold fever. This herb tastes bitter, has a slightly cold qi, and is fragrant and dispersing. It is especially good at evacuating the evil in half of Shaoyang and half of the inside. It is used to treat evil in Shaoyang, alternating chills and fever, fullness and discomfort in chest and hypochondrium, bitter taste in mouth and throat. As an important medicine for shaoyang syndrome/pattern, it is often used with Skullcap Root, such as Minor Bupleurum Decoction; it is used to treat common cold fever, and this product also has good evacuation. For antipyretic effect, it is often used together with Liquorice Root. If the heat evil is severe, it can be used with Pueraria Root, Skullcap Root, Gypsum is equivalent to Bupleurum and Pueraria Flesh-Releasing Decoction; the existing single-flavor or compound formula injections made of Bupleurum are more effective for external-contraction fever. Good antipyretic effect.
2. Used for liver depression, stagnation, menstrual irregularities, chest and hypochondrium pain. This product can relieve liver qi, soothing liver and relieving depression, regulate menstruation and relieve pain. It is often used with Chinese Angelica and Peony Root, such as Peripatetic Powder ; For chest and hypochondrium pain, it can be used regardless of internal damage, liver depression, trauma or fall. It is often used with Cyperus, Sichuan Lovage Rhizome, Peony Root is equivalent to Bupleurum Liver-Soothing Powder.
3. It is used for qi deficiency, chronic diarrhea prolapse of rectum, this product is good at lifting the Qi of the spleen and stomach to clear yang, and is good at treating qi deficiency, fatigue, loose stool, chronic diarrhea prolapse of rectum, stomach and uterus prolapse, etc. It is often used with Ginseng, Astragalus Root, Cimicifuga Rhizome, etc., such as Middle-Tonifying Qi-Replenishing Decoction .
4. In addition, this product can also reduce fever and prevent attack of malaria. It is also a commonly used product for treating malaria Hanre. It is often used with Skullcap Root and Dichroa, Caoguo and the like can be used.

[Documentation]

1. Benjing: "It regulates qi in the intestines and stomach, drink food accumulation, Hanre pathogenic qi, promote the new."
2. Bencaozheng Yi : "Roughly speaking, Bupleurum is the main treatment, and there are two levels. One is the actual evil, which is the external evil that is half on the outside and half on the inside. It is led out, so that it reaches the outside and the external evil spontaneously occurs; The first is positive deficiency, which means clearing the qi aspect of the person trapped in the yin part, lifting it up, and returning it to its home, and the middle qi will revive on its own."

Traditional Chinese medicine can effectively treat dry eye syndrome, floaters, retinopathy, and various chronic eye diseases

[Usage and Dosage]

Decoct and take, 3~10g. It should be used raw to relieve and relieve fever, to be boiled with vinegar to relieve liver depression, and to be stir-fried with turtle blood for steaming bone fever.

[Precaution]

Bupleurum Xing Sheng Powder, the ancients said "Bupleurum robs liver yin", if ascendant hyperactivity of liver yang, internal stirring of liver wind, yin deficiency with effulgent fire and qi movement, it should be avoided or used with caution.

[Modern Pharmacology]

Bupleurum root contains α-spinachsterol, catholol and bupleurum saponins, as well as volatile oils. Bupleurum angustifolia roots contain saponins, volatile oils, Bupleurum alcohol, Phyllostachys alcohol, and alpha-spinasterol.

1. It has obvious antipyretic, sedative, analgesic and antitussive effects. The main active ingredient is saponin, and the volatile oil also has antipyretic effects.
2. Volatile oil also has the effect of fighting common cold viruses and enhancing the body's immunity.
3. The anti-inflammatory strength of Bupleurum saponin is similar to that of prednisolone, and its anti-granulomatous proliferation is stronger than its anti-exudation effect. The anti-inflammatory effect is relatively complex. In addition to stimulating the adrenal cortex, it also has certain effects on many aspects such as infiltration of the inflammatory process, increased capillary permeability, release of inflammatory mediators, migration of white blood cells, and connective tissue hyperplasia. Impact.
4. It has obvious hepatoprotective and choleretic effects. Bupleurum has obvious antagonistic effects on experimental liver damage in animals caused by carbon tetrachloride, etc. For example, the combination of medicinals Liquorice Root (Gan Chai Mixture) is more effective. The choleretic effects may be flavonoids. Bupleurum also has certain anti-ulcer effects, and Bupleurum crude saponins have preventive and therapeutic effects on experimental gastric ulcers in animals.
5. Has the effect of lowering blood lipids. And its effect on triglycerides is more obvious than that on cholesterol. The main components that affect lipid metabolism are sapogenins a and d.
6. Bupleurum may enhance humoral and cellular immunity and increase protein biosynthesis in rats.
7. decoction has certain inhibitory effects on hemolytic streptococci, vibrio cholera, subcutaneous node bacilli and leptospira. It also has a strong inhibitory effect on influenza virus, as well as anti-hepatitis virus and inhibition of cytopathic effects caused by type I myelitis virus. Bupleurum may also have anti-plasmodial effects.
8. Bupleurum saponin has strong side effects such as hemolysis and local irritation, and there are reports of allergic reactions caused by Bupleurum injection.

[Modern Application]

1. For common cold. Take Zheng Bupleurum drink (Bupleurum, Saposhnikovia Root, Dried Tangerine Peel, Peony Root, Liquorice Root, Fresh Ginger Rhizome) 3 times a day, 12 grams each time, to treat 666 cases, with an effective rate of 79%, which is better than the Isatis Root group (238 cases , effective rate 54.6%) [Bupleurum Drink Clinical Validation Collaboration Group. Clinical observation on the treatment of common cold with Bupleurum drink. Journal of Traditional Chinese Medicine 1985;12:13].
2. For cough. Bupleurum antitussive tablets (made from the active ingredients extracted from the residue of Bupleurum injection) were used to treat 1005 cases of cough caused by common cold, acute and chronic tracheitis, pneumonia, lung cancer, etc., with a total effective rate of 85.8% [天眼Light, wait. Study on the clinical efficacy of Bupleurum antitussive tablets. Hiroshi Medicine 1987;4:41].
3. For infectious hepatitis. Take Ganchai mixture (half and half Liquorice Root and Bupleurum), 10 ml each time, 3 times a day (equivalent to 15 grams each of Liquorice Root and Bupleurum), half the amount in children, and treated 11 cases with satisfactory results, especially for reducing alanine aminotransferase. More prominent [Shanxi Medical College Liver Disease Research Group, etc. Clinical observation on the enzyme-lowering effect of Ganchai Mixture and Forsythia syrup on acute infectious hepatitis. Journal of New Medicine 1974,2:18]. Experimental observations on rats show that Ganchai mixture has a preventive and therapeutic effect on experimental liver cirrhosis. It can prevent the accumulation of fat in the liver, inhibit fiber proliferation, and promote fiber reabsorption [Liver Disease Research Group of Shanxi Medical College. Observation on the preventive and therapeutic effects of Ganchai Mixture on experimental liver cirrhosis. Journal of New Medicine 1974,2:28].
4. For hyperlipidemia. 86 cases were treated with 20 ml of lipid-lowering mixture (equivalent to 3 grams of Bupleurum, plus Grosvenor Momordica Fruit for flavoring), 3 times a day, 3 weeks of treatment, and had a good effect on lowering triglycerides [Li Zongji, et al. Observation on the efficacy of Bupleurum in lowering blood lipids. Journal of Traditional Chinese Medicine 1988;2:62].
5. For herpes simplex keratitis. Use Bupleurum injection (10% solution) for eye drops, once an hour; intramuscular membrane injection, 0.3~0.5 ml each time, once every other day; intramuscular injection 2 ml each time, 1~2 times a day, three methods of treatment 18 cases were treated for an average of 16 days and all recovered [Wu Dejiu. Clinical observation on the treatment of herpes simplex keratitis with Bupleurum injection. Chinese herbal medicine communication 1978,12:29].
6. For erythema multiforme. Inject Bupleurum injection intramuscularly, 2 ml each time (equivalent to 4 grams of crude drug), twice a day for 10 days. 13 cases were observed and all recovered [Liu Pengfei. Introduction of 13 cases of Bupleurum in the treatment of erythema multiforme. skin disease Control Research Letters 1979;2:1l0)
7. For plum-stone qi (globus hystericus). Inject 2 ml of Bupleurum injection into Tiantu point, once a day or every other day, 4 times as a course of treatment, 25 cases were treated, 15 cases were cured, 6 cases improved, and 4 cases were ineffective [Lu Xihua. Bupleurum acupuncture treatment for plum-stone qi (globus hystericus)． Journal of Zhejiang Academy of Chinese Medicine 1987;6:52].