The book was written by Sun Si-miao and was completed around the second year of Yongchun (682). The author compiled nearly thirty years of experience in his later years to supplement the shortcomings of his earlier monumental work Qianjin Yaofang, hence the name "Yifang" (Wing Formula).

This book consists of 30 volumes. During the Northern Song period, the Bureau for the Correction of Medical Texts revised its transmitted versions and published them nationwide. From the Song dynasty to the present, nearly twenty editions have been printed and reproduced in China. In addition to treasuring six Chinese editions, Japan also has two better versions of its own reprints. Among the existing editions, the one printed by Wang Ken-tang in the 33rd year of Wanli (1605) is considered the best. The 1955 reprint by the People's Medical Publishing House, based on the Edo medical edition, is more commonly seen.

Qianjin Yifang consists of 30 volumes, covering 189 categories, with a total of over 2,900 prescriptions, theories, and methods. Volumes 1 to 4 discuss medicinal substances, citing most of the content from Tang Bencao. Volumes 5 to 6 cover women's diseases; volumes 9 to 10 discuss cold-damage disease; volume 11 deals with pediatric diseases; and volumes 12 to 15 elaborate on health preservation and longevity, embodying the ancient theory of prolonging life combined with disease prevention and treatment. Volumes 16 to 25 discuss apoplexy, miscellaneous diseases, high fever, epididymitis, and orchitis, among others; volumes 26 to 28 cover acupuncture and moxibustion; and volumes 29 to 30 are on forbidden texts, which, although containing incantation techniques, also include content on psychotherapy.

Qianjin Yifang systematically discusses the six-meridian differentiation of cold-damage disease, internal miscellaneous diseases, external sores and swellings, diagnosis through observation, differentiation of yin-yang, exterior-interior, deficiency-excess, and treatment techniques, providing valuable experience in these areas.

This book, along with Beiji Qianjin Yaofang, is hailed as an encyclopedia of clinical medicine in China and has had a profound influence on the history of Chinese medicine.