Astragalus 120 gm (raw), Dang Gui Wei 6 gm, Red Peony 4.5 gm, Earthworm 3 gm (de-soiled), Chuan Xiong 3 gm, Peach Kernel 3 gm, Safflower 3 gm.

bubble_chart Preparation and Dosage

decocted in water for administration .

bubble_chart Efficacy

Replenishing qi and invigorating blood, dispelling stasis to unblock collaterals.

bubble_chart Indications

Sequelae of wind stroke. Deficiency of healthy qi, stasis in the collaterals, hemiplegia, deviated mouth and eyes, sluggish speech, drooling, dry stool, frequent urination, or incontinence, white tongue coating, slow pulse. Currently used for sequelae of cerebrovascular accidents, sequelae of poliomyelitis, and hemiplegia or paraplegia caused by other reasons, belonging to qi deficiency and blood stasis.

bubble_chart Formula Principles

This formula heavily utilizes Astragalus Root for its potent tonification of primordial qi; Chinese Angelica Tail, Sichuan Lovage Rhizome, Red Peony Root, Peach Kernel, and Carthamus to invigorate blood and resolve stasis; and Earthworm to unblock meridians. The combination of these herbs promotes vigorous qi and smooth blood flow, dispels stasis, and unblocks meridians, thereby gradually alleviating various symptoms.

bubble_chart Formula Modification

Initially diagnosed with hemiplegia, add 3 grams of Saposhnikovia Root according to this prescription and take it for four to five doses before discontinuing. If the illness has persisted for two to three months and previous treatments followed ancient prescriptions using excessive cold and cooling herbs, add 12-15 grams of Aconite Lateral Root. If excessive wind-dispelling herbs were used, add 10-15 grams of Tangshen.

Apoplexy with healthy qi not deficient or yin deficiency with yang hyperactivity, and when wind, fire, phlegm, dampness, and other residual pathogens are not completely resolved, are contraindicated.

bubble_chart Modern Pharmacology

1. Effect on Hemorheology "Zhejiang Journal of Traditional Chinese Medicine 1986(3):110", the blood of apoplexy patients tends to be "sticky, thick, coagulated, and aggregated". After using this prescription, it can increase the content of cyclic adenosine monophosphate in platelets, inhibit platelet aggregation and release reactions, and inhibit and dissolve thrombi to improve microcirculation.
2. Pharmacological Effects on the Cardiovascular and Cerebrovascular Systems "Chinese Medicinals Bulletin 1987(2):51", intravenous injection of Yang-Tonifying Five-Returning Decoction has a slow and long-lasting antihypertensive effect. It significantly enhances the myocardial contraction amplitude in anesthetized rabbits, significantly reduces the myocardial tension-time index reflecting myocardial oxygen consumption, and significantly increases myocardial nutritional blood flow.
3. Effect on Immune Function "Shaanxi Chinese Medicine 1986(10):466", Yang-Tonifying Five-Returning Decoction can increase the weight of immune organs in mice with low immune function and enhance the phagocytic function of mononuclear macrophages, indicating that this prescription has a pharmacological basis for enhancing the body's immune function.