Astragalus 3 gm, Licorice (roasted) 1.5 gm, Ginseng (de-reeded) 0.9 gm, Angelica root 0.6 gm (baked dry with wine or sun-dried), Tangerine peel (white part removed) 0.6～0.9 gm, Cimicifuga 0.6～0.9 gm, Bupleurum 0.6～0.9 gm, Atractylodes 0.9 gm.

bubble_chart Preparation and Dosage

The above ingredients are finely chewed and merged into a potion. Use 300 ml of water, boil until reduced to 150 ml, remove the dregs, and administer while lukewarm before meals.

bubble_chart Efficacy

Tonifying middle and replenishing qi, raising yang and elevating the drooping.

bubble_chart Indications

Spleen and stomach qi deficiency, lack of qi, reluctance to speak, weakness in the limbs, fatigue and reduced appetite, bland taste in food, intolerance to fatigue, shortness of breath upon exertion; or qi-deficiency fever, high breathing and panting, body heat and irritability, thirst with a preference for hot drinks, a pulse that is strong and large but weak upon pressure, skin unable to withstand wind-cold, resulting in chills, fever, and headache; or qi deficiency causing sinking, chronic diarrhea, rectal prolapse. Currently used for uterine prolapse, gastroptosis, or other visceral prolapse.

bubble_chart Formula Principles

In the formula, Astragalus Root serves as the monarch herb, tonifying the middle and replenishing qi, raising yang and securing the exterior. Ginseng, White Atractylodes Rhizome, and Liquorice Root, with their sweet and warm properties, tonify qi and strengthen the spleen and stomach, acting as the minister herbs. Dried Tangerine Peel regulates qi movement, while Chinese Angelica tonifies blood and harmonizes the nutrient level, serving as the assistant herbs. Cimicifuga Rhizome and Bupleurum work together with Ginseng and Astragalus to uplift clear yang, acting as the envoy herbs. Overall, the formula tonifies qi and invigorates the spleen, ensuring the source of postnatal generation and transformation, thereby curing various syndromes of spleen and stomach qi deficiency. Additionally, it uplifts the middle qi, restoring the ascending and descending functions of the middle energizer, allowing conditions of prolapse and sinking to return to their proper positions.

For severe illness with fatigue and excessive heat, increase Astragalus Root to 3 grams; for cough, remove Ginseng; for abdominal pain, add Peony Root 1.5 grams and Prepared Liquorice Root 1.5 grams; if there is aversion to heat, preference for cold, and abdominal pain, add Skullcap Root 0.6～0.9 grams; for aversion to cold and cold pain, add Cassia Central Bark 0.3～0.9 grams; for headache, add Chastetree Fruit 0.6～0.9 grams; for severe pain, add Sichuan Lovage Rhizome 0.6 grams; for top of the head pain and brain pain, add Chinese Lovage 0.9～1.5 grams.

bubble_chart Cautions and Contraindications

Those with yin deficiency and internal heat should avoid taking it.

bubble_chart Modern Pharmacology

1. Pharmacological effects on different organs such as the uterus, myocardium, and small intestine. "Tianjin Medical Journal" 1960(1):4-12. This formula has a selective excitatory effect on the in vivo or in vitro uterus and its surrounding tissues, especially when combined with motherwort herb and Submature Bitter Orange, the effect is more pronounced. A small amount of Middle-Tonifying Qi-Replenishing Decoction can excite the myocardium, while an excessive amount shows an inhibitory effect. The effect on the small intestine is more complex; when peristalsis is hyperactive, it shows an inhibitory effect, slowing down peristalsis and reducing tension; when the intestine is in a state of inhibition, it enhances peristalsis. This confirms that the formula has a bidirectional regulatory effect. From the experiments, it can also be seen that in preparations containing Cimicifuga Rhizome and Bupleurum, the effect on animals is significant. When Cimicifuga Rhizome and Bupleurum are removed, the effect weakens, indicating that these two drugs can enhance the effect of other drugs, especially on intestinal peristalsis.
2. Anti-genetic mutation and anti-tumor effects. "Chinese Patent Drug Research" 1985(12):27. The anti-genetic mutation and anti-tumor effects of this formula are stronger than those of Four Gentlemen Decoction. At the same time, this formula can also regulate the body's immune function and prolong the survival time of animals. This suggests that when using anti-tumor chemotherapy drugs clinically, combining them with this formula can improve efficacy and reduce the toxic side effects of chemotherapy drugs.