Yibian
 Shen Yaozi 
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formulaAnti Diphtheria Mixture Kang Bai Hou He Ji
source"Famous Prescriptions past and Present" Citing the Tianjin Infectious Disease Hospital Formula
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bubble_chart Composition

Rehmannia 10.5 gm, Scrophularia 15 gm, Ophiopogon 9 gm, Scutellaria and Forsythia 18 gm each.

bubble_chart Preparation and Dosage

The above ingredients are prepared into a mixture of 60 ml. For those over 10 years old, take 25 ml each time, four times a day, reducing to twice a day after two days. For those under 10 years old, take 15-20 ml each time.

bubble_chart Efficacy

Nourishing yin, benefiting the pharynx, clearing heat, and removing toxins.

bubble_chart Indications

Diphtheria, acute pharyngitis, acute tonsillitis, and scarlet fever.

bubble_chart Modern Pharmacology

Toxicity and Antibacterial Effects "Tianjin Medical Journal" 1966(4):243-244. The determination of the median lethal dose (LD50) of this mixture in guinea pigs demonstrated its low toxicity. Multiple bacteriostatic and antitoxin tests confirmed that in vitro, the bacteriostatic effect against diphtheria bacilli was 100 IU/mL, the bactericidal effect was 200 IU/mL, and the toxin-neutralizing effect was 2000 MRD/mL.

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