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Yibian
 Shen Yaozi 
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formulaHongsheng Pill Hong Sheng Dan
sourceJinzong Jinjian Volume 62
smart_toy
bubble_chart Composition

Cinnabar 15 gm, Realgar 15 gm, Mercury 3 gm, Saltpeter 120 gm, Alum 30 gm, Vitriol 18 gm

bubble_chart Preparation and Dosage

First, grind alum, green vitriol, and saltpeter into a fine powder and mix well. Place the mixture into a large copper spoon, add 150 ml of fire wine, and heat until dissolved. Once dry, remove and grind into a fine powder. Separately, grind mercury, cinnabar, and realgar into a fine powder until no visible particles remain, then mix with the previously prepared alum and saltpeter powder. Coat the inner wall of the Yangcheng jar with a 1 cm thick layer of paper pulp mud and let it dry in the shade, ensuring no cracks form. Place the prepared mixture into the jar, seal the jar tightly, and secure the jar's mouth with cotton paper strips dipped in honey to fill any gaps. Externally, seal the jar with a mixture of calcined gypsum powder and vinegar. Then, place the jar directly over charcoal fire to heat. Start with a low flame (flame not rising) for half an hour; then use a medium flame (flame reaching halfway up the jar) for another half hour, while occasionally wiping the jar lid with a wet brush. Finally, use a high flame (flame level with the jar's mouth) for the last half hour. After removing from heat and allowing it to cool, open the jar lid and scrape off the medicinal powder from the lid, grinding it finely for later use. Apply a small amount to the wound, cover with a medicated plaster, or wrap with gauze.

bubble_chart Efficacy

Drawing out toxins to remove decay and promote muscle regeneration.

bubble_chart Indications

After the ulcer bursts, the wound becomes hard, and the flesh turns dark purple and black.

bubble_chart Modern Pharmacology

Toxic effects: "Tianjin Chinese Medicine" 1986 (4):24. The median lethal dose (LD50) of this formula administered orally to mice at one time was 120.98±1.71 mg/kg. According to the classification of acute toxicity, it is a moderately toxic drug. When applied to local skin wounds, it was proven that mercury compounds in the formula could be absorbed from the wound, with the highest mercury content found in the kidneys. The toxicity of this formula is cumulative, classified as grade I accumulation, but it is close to the moderate accumulation coefficient, which may be the cause of clinical chronic poisoning.

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