Rehmannia glutinosa (prepared) 30 gm, Ephedra 1.5 gm, Cervi Cornus Colla 9 gm, Sinapis alba 6 gm (stir-fried, ground), Cinnamomum cassia 3 gm, Glycyrrhiza uralensis (raw) 3 gm, prepared Zingiber officinale (charred) 1.5 gm.

bubble_chart Preparation and Dosage

decocted in water for administration .

bubble_chart Efficacy

Warming yang, tonifying blood, dispersing cold, and unblocking stagnation.

bubble_chart Indications

Multiple abscesses, yin gangrene, digital gangrene, crane knee wind, stony nodules, and bone-attached gangrene caused by yang deficiency and cold congealment, characterized by diffuse swelling without a head, flat and sunken, unchanged skin color, soreness and pain without heat, no thirst, pale tongue with white coating. Currently used for subcutaneous bone nodes, chronic osteomyelitis, periostitis, chronic lymphadenitis, rheumatoid arthritis, aseptic deep muscle abscesses, sciatica, thromboangiitis obliterans, chronic bronchitis, chronic bronchial asthma, abdominal subcutaneous nodes, women's breast lobular hyperplasia, dysmenorrhea, and other conditions attributed to yang deficiency and cold congealment.

bubble_chart Formula Principles

The formula heavily uses Prepared Rehmannia Root to greatly nourish nutrient-blood as the sovereign; Cervi Deer-Horn Glue to generate essence, replenish marrow, nourish blood, and warm yang as the minister; Carbonized Ginger to break yin and harmonize yang, Cassia Bark to warm the meridians and unblock the vessels, White Mustard Seed to disperse phlegm and dissipate nodules, and Ephedra to regulate the blood vessels and unblock the striae and interstices, all serving as assistants; Raw Liquorice Root to resolve pus toxins and harmonize the various herbs as the envoy. When these herbs are combined, yang returns and yin dissipates, the blood vessels are unblocked, and it is used for conditions of pudendal coldness, akin to the sun shining in the sky and dispersing the gloomy haze, hence the name "Yang-Harmonizing Decoction."

Sore and ulcer yang pattern, yin deficiency, and those with prolonged heat and ulceration should avoid use.

bubble_chart Modern Pharmacology

The inhibitory effect on subcutaneous node bacteria. "Research on Chinese Patent Medicine" 1981(11):41. According to antibacterial tests conducted on sputum cultures from 5 cases of stubborn subcutaneous node, it was confirmed that this prescription indeed has an inhibitory effect on subcutaneous node bacteria. However, when the seven drugs in the prescription were used individually, they either had no effect or the effect was not significant.