Traditional Chinese Medicine believes that this disease falls under the categories of "asthma," "abdominal pain," "blood deficiency," "phlegm rash," and "worm pattern." The disease's etiology and pathogenesis are primarily due to congenital insufficiency and improper postnatal care, leading to a deficiency in nutrient-defense, invasion of the body by wind-cold and dampness-heat pathogens, which accumulate in the lungs causing cough and asthma, and manifest on the skin as phlegm rash and cutaneous pruritus. Alternatively, excessive consumption of rich, fatty foods, fish, shrimp, crab, and other items that promote wind and dampness can lead to the accumulation of wind, dampness, and heat in the stomach and intestines, manifesting on the skin as urticaria. Prolonged illness can lead to spleen and kidney deficiency, resulting in symptoms of blood deficiency.

bubble_chart Modern Research

Eosinophilia refers to eosinophils accounting for more than 6% of the white blood cell differential count in adult peripheral blood, or an absolute value exceeding 440 per cubic millimeter. Its clinical manifestations are mostly determined by the primary disease. Common symptoms include cough, expectoration, asthma, chest tightness, fever, rash, loss of appetite, abdominal pain, dizziness, weight loss, or anemia.

The main disease causes of eosinophilia include: Chinese Taxillus Herb infestation, allergic diseases, skin diseases, pulmonary eosinophilia, hematological diseases, physical and chemical factors, certain pestilence diseases, malignant tumors, familial eosinophilia, and eosinophilic lymphogranuloma.

Eosinophilia caused by allergic reactions is due to the body's allergic reaction to foreign protein antigens, which causes sensitized tissue cells to release histamine and eosinophil chemotactic factors. Eosinophils, on one hand, neutralize histamine, and on the other hand, are attracted by eosinophil chemotactic factors, leading to an increase in peripheral blood eosinophils.

1. Symptoms: The onset is slow, with self-reported fatigue, weakness, anorexia, low-grade fever, and fear of cold. After one week, a cough begins, mostly paroxysmal, with little sputum that is difficult to expectorate, appearing as white sticky sputum. Shortness of breath, difficulty breathing, similar to an asthma attack, often worsens at night. Some may experience abdominal pain and skin rashes.
2. Signs: Lung qi swelling and diffuse bronchitis signs may be present, with possible cyanosis. During the fever period, a few patients may have hepatosplenomegaly or lymphadenopathy.
3. Laboratory tests:
   1. Blood picture: Increased white blood cells, significantly elevated eosinophils (20%-80%), and accelerated erythrocyte sedimentation rate.
   2. Syphilis blood moistening and tonifying body binding reaction: 60% positive, cold agglutination test, mostly highly positive; heterophile agglutination test, 1/3 may be positive.
   3. Sputum examination: Increased eosinophils.

bubble_chart Pattern Analysis

1. Invasion of the Lung by External Pathogens︰Fever, fear of cold, cough, expectoration of white sticky phlegm, panting or asthma, especially severe at night. Spontaneous sweating, itchy skin, rashes or urticaria, or facial and lower limb edema. Pale tongue with thin white coating, floating and rapid pulse. Dispersing wind and clearing heat, ventilating the lung and releasing the exterior. Modified Xiaofeng Qingre Decoction. Schizonepeta 10g, Saposhnikovia Root 10g, Cicada Slough 10g, Skullcap Root 15g, White Mulberry Root-Bark 15g, Sophora 15g, Dyers Woad Leaf 30g, Chinese Angelica 10g, Liquorice Root 6g, Arnebia 30g. For severe asthma, add Pepperweed Seed 15g, Perilla Fruit 15g; for paroxysmal cough with expectoration of white sticky phlegm, add Belamcanda Rhizome 10g, Aster 10g, Coltsfoot Flower 10g; if urticaria is predominant with pale color and no redness, add Cinnamon Twig 10g, Peony Root 10g.
2. Dampness-heat of Spleen and Stomach︰Abdominal pain, gastric stuffiness, nausea and vomiting, anorexia, diarrhea or constipation, shortness of breath and chest tightness, cutaneous pruritus, urticaria or hives, even fever, general weakness and fatigue. Pale and swollen tongue with yellow greasy coating, slippery and rapid pulse. Clearing heat and draining dampness, downbearing counterflow to stop vomiting. Modified Huo Po Xia Lou Tang. Patchouli 10g, Magnolia Bark 10g, Pinellia Rhizome 10g, Trichosanthis Fruit 10g, Pueraria Root 15g, Forsythia 15g, Sophora 15g, Densefruit Pittany Root-bark 15g, Belvedere Fruit 15g, Immature Orange Fruit 30g, Liquorice Root 6g. For severe abdominal distension, fullness, pain, or constipation, add Raw Rhubarb Rhizome (to be decocted later) 10g; for high fever, add Raw Gypsum 20g; for severe vomiting, add Bamboo Shavings 15g and Coptis Rhizome 6g.
3. Spleen-kidney Yang Deficiency︰Dizziness, lack of strength, tinnitus, lumbago, mental fatigue, shortness of breath, panting or asthma upon exertion, anorexia, nausea with a tendency to vomit, fear of cold, cold limbs, loose stools, occasional cutaneous pruritus. Pale tongue with thin white coating, deep and thin pulse. Warm the kidneys and strengthen the spleen, tonify and replenish qi and blood. Modified Aconite Middle-Regulating Decoction: Prepared Aconite Root 15g, Codonopsis Root 15g, Dried Ginger 10g, White Atractylodes Rhizome 10g, Immature Orange Fruit 30g, Barbary Wolfberry Fruit 10g, Cornus Fruit 10g, Chinese Angelica 10g, Epimedium Herb 15g, Peony Root 10g, Liquorice Root 6g. For those with abdominal pain and diarrhea, add Hawthorn Fruit 10g, Medicated Leaven 10g, Dried Tangerine Peel 10g, Aucklandia Root 10g; for cases caused by ascariasis, add Quisqualis Fruit 10g, Sichuan Chinaberry Bark 10g; for those with dampness, add Notopterygium 10g, Pubescent Angelica 10g, and remove Peony Root and Barbary Wolfberry Fruit.