Pancreas Bile Syndrome, also known as pancreatic malignant sexually transmitted disease syndrome or pancreatic head cancer obstructive jaundice syndrome, was first described by Bard and Pic in 1888, hence also referred to as Bard-Pic syndrome.

bubble_chart Clinical Manifestations

Cancer of the head of the pancreas compresses and causes common bile duct obstruction, presenting as progressive painless jaundice with gallbladder enlargement and hepatomegaly. The intestinal tract contains very little bile, resulting in grayish-white stools. Digestive symptoms such as epigastric or left upper abdominal distension and fullness pain are common, along with possible nausea, vomiting, abdominal distension and fullness, and weight loss. Sometimes, enlarged supraclavicular lymph nodes can be palpated, and ascites or diabetes may also occur. Blood amylase levels are elevated. Advanced stages often present with cachexia.

bubble_chart Auxiliary Examination

1. Hypotonic X-ray duodenography shows enlargement and displacement of the duodenal loop.

2. Type B ultrasound and CT scans reveal pancreatic enlargement and space-occupying lesions.

bubble_chart Diagnosis

The diagnosis can be made by combining X-ray duodenography, B-mode ultrasound, and CT scans. ERCP examination aids in the diagnosis of pancreatic tumors.

bubble_chart Treatment Measures

The main treatment approach is surgery, aiming for a cure in combination with chemotherapy, radiotherapy, and immunotherapy.