The onset of this disease may be related to endocrine or microcirculation disorders. Physical or chemical stimuli, such as alkaline solution washing or exposure to organic solvents, can easily induce the disease. It occurs more frequently in women, hence it is considered a subtype of housewife's dermatitis.

bubble_chart Clinical Manifestations

1. It commonly occurs in young women, manifesting as dry and rough skin damage, grade I erythema and desquamation, with loss of fingerprints. In severe cases, the skin thickens and rhagades may develop, often without subjective symptoms;
2. The lesions typically first appear on the thumb, index finger, and middle finger, later affecting the ring finger and little finger;
3. Symptoms worsen in winter and may lead to rhagades, aggravated by contact with alkaline substances such as soap and detergent.

bubble_chart Diagnosis

1. It commonly occurs in young women, with typical lesions on the palms and fingers.
2. It often develops or worsens after physical or chemical stimulation.

bubble_chart Treatment Measures

Treatment Principles

1. Avoid contact with alkaline substances such as soap, laundry detergent, dishwashing liquid, and organic solvents;
2. Try taking vitamin A and vitamin E, and apply vitamin A acid ointment externally;
3. Superficial X-ray local irradiation may be attempted;
4. Apply 5% sulfur cream, salicylic acid ointment, urea, or corticosteroid ointment as appropriate.

1. For mild cases, use hormone ointment containing urea externally and take vitamin A and vitamin B orally.
2. If symptoms worsen in winter or are related to microcirculation disorders, calcium antagonists such as nifedipine may be added to dilate blood vessels.

bubble_chart Cure Criteria

1. Cure: More than 90% of skin lesions have subsided;
2. Improvement: More than 30% of skin lesions have subsided, or rhagade has disappeared;
3. No cure: Less than 30% of skin lesions have subsided, or rhagade has worsened.