Autoimmune eczema, also known as autosensitization dermatitis, is an inflammatory reaction caused by the patient's allergic response to certain substances formed after stimulation of their own skin disease. Patients initially have primary sources such as nummular eczema, contact dermatitis, stasis dermatitis, chronic ulcers, or hematomas. Often due to improper treatment, excessive physical or chemical stimulation, bacterial infections, or the formation of antigens from protein breakdown products, autosensitization occurs. This condition is more common in middle-aged and elderly individuals, and diagnosis is not difficult. Treatment includes rest, taking sedative and antipruritic medications, and maintaining cleanliness. Antibiotics are used when infection is present, and short-term corticosteroid therapy can yield excellent results for severe or widespread cases.

bubble_chart Clinical Manifestations

1. The primary lesion acutely worsens, presenting with redness, swelling, erosion, and exudation, predominantly on the lower legs and feet;
2. After 1–2 weeks, secondary lesions appear, manifesting as papules, small chickenpox-like lesions, erosions, and exudation;
3. The distribution is mainly on the limbs, especially the upper limbs, but can also occur on the trunk, face, and neck;
4. Cutaneous pruritus is severe.

bubble_chart Diagnosis

1. Primary lesion source acutely worsens;
2. 1 to 2 weeks later, the disease occurs at a site distant from the primary source;
3. Skin lesions: erythema, papule, chickenpox, erosion, exudation;
4. Severe itching.

bubble_chart Treatment Measures

Treatment Principles

1. Treat the primary source;
2. Antibiotic therapy;
3. Antihistamine therapy;
4. Corticosteroid therapy;
5. Topical Yaodui treatment.

1. For mild cases, primarily use oral chlorpheniramine, prednisone, and topical medications;
2. For cases with extensive skin lesions, cetirizine or loratadine + oral prednisone and topical medications are preferred;
3. For severe cases, intravenous dexamethasone, fluid replacement, prevention of complications, and selection of effective antihistamines (including newer drugs) are recommended.{|}

   bubble_chart Cure Criteria

   1. Cure: Symptoms and signs disappear, skin lesions subside;
   2. Improvement: Symptoms and signs improve, skin lesions subside by more than 75%;
   3. No cure: Symptoms and signs show no improvement, skin lesions remain unchanged.