Seborrheic keratosis, also known as senile keratosis, is a very common benign skin tumor in middle-aged and older individuals, affecting both men and women equally. The condition progresses slowly and persists for years without resolution, but it rarely becomes cancerous. There is a clear genetic predisposition, and it may also be associated with long-term sun exposure. A sudden increase in number or size may indicate malignancy, particularly gastrointestinal tumors.

bubble_chart Diagnosis

Clinical manifestations 1. Lesions commonly occur on the face, especially the temporal region, followed by the back of the hands, trunk, and limbs; 2. Initially appearing as light brown, dark brown, or black, flat papules that slowly enlarge, with a rough surface or papillomatous hyperplasia, often accompanied by greasy scales, and varying in number; 3. The sudden appearance of multiple seborrheic keratosis-like skin lesions in a short period may be associated with internal malignant tumors.

Diagnostic criteria 1. Typical skin lesions with a "stuck-on" appearance in common sites; 2. Histopathology: Hyperkeratosis and papillomatous hyperplasia, with visible keratin cysts, and tumor cells composed of basaloid cells.

bubble_chart Treatment Measures

Treatment Principles 1. It is a benign tumor and generally does not require treatment; 2. If necessary, apply 5-Fu ointment externally, cryotherapy, or laser therapy; 3. For suspected malignant transformation, surgical treatment and pathological examination are required.

Medication Principles Drug treatment can only involve the external use of 5-fluorouracil, as this medication only clears the lesions and generally does not harm normal skin. Temporary pigmentation may occur at the application site.

1. Cure: The skin lesions are basically cleared without leaving scars; 2. Improvement: The skin lesions are reduced or cleared, but with significant scarring; 3. No cure: The skin lesions show no change.