Atopic dermatitis is a chronic, recurrent, pruritic, inflammatory skin disease associated with heredity, characterized by a tendency to produce IgE and often accompanied by asthma and allergic rhinitis. The skin of patients exhibits the following features: pale and dry skin, keratosis pilaris, ichthyosis-like changes on the lower limbs, infraorbital folds, fine and numerous palmar creases, lower skin temperature on fingers (toes), and reduced sweating. The inheritance pattern remains unclear. The disease begins in infancy, persists through childhood into adulthood, and involves long-term recurrent episodes. However, not all cases clinically progress through all three stages. Certain foods, Mongolian snakegourd root, animal skin and hair, or seasonal changes can influence the condition. Eliminating triggering factors and symptomatic treatment can lead to recovery.

bubble_chart Diagnosis

Clinical manifestations 1. Skin lesions: erythema, papule, scale, lichenification; 2. Severe itching; 3. Accompanied by xeroderma, ichthyosis, palmar hyperlinearity, etc.

Diagnostic basis 1. Rash exhibits age-related staging; 2. Skin lesions present as erythema, papule, scale, lichenification; 3. Family or personal history of atopic diseases; 4. Severe itching; 5. Accompanied by xeroderma, ichthyosis, palmar hyperlinearity, etc.

bubble_chart Treatment Measures

Treatment Principles 1. For infant patients, topical medications are the mainstay, primarily aimed at relieving itching. 2. For young children and adults, oral medications and topical treatments can be used simultaneously.

Medication Principles 1. For infant cases, chlorpheniramine and topical medications are the main treatments. 2. For childhood, adolescent, and adult cases with widespread rashes, cetirizine or clemastine + prednisone and topical medications are preferred.

1. Cure: Symptoms and signs disappear, skin lesions completely subside; 2. Improvement: Symptoms and signs improve, skin lesions subside by more than 75%; 3. No cure: Symptoms and signs do not improve, skin lesions remain unchanged.