Zhang, male, approximately over eighty years old, was diagnosed in the winter of 1974. The patient's lower limbs were cold from below the knees to the feet, with a purplish-dark color on both feet. The skin near the toes was dry and withered, resembling thick dead skin, and there were several scattered small ulcers on the surface, but not very painful. The pulse manifestation was slow and thin.

This was due to the winter of 1974 being colder and longer than previous years. Although the patient slept on a heated brick bed, the heat was insufficient, and the temperature at the edges where the feet extended was even lower. The bedding was not thick enough, so the feet did not receive adequate warmth. Additionally, the patient was elderly and disliked getting out of bed to move around. Combined with the above reasons, this led to poor blood circulation, and pudendal coldness congealed and stagnated, resulting in this condition. The treatment should focus on warming the meridians and invigorating the blood. The prescription used was the original formula of Angelica Cold-Extremities Decoction with the addition of Carthamus. Since the patient had difficulty decocting the medicine, it was ground into a fine powder. Two qian of the powder was taken each time, infused with boiling water, once in the morning and once in the evening.

After finishing one dose, the color of the legs became lively and red, and the coldness also lessened. Another dose was taken, and the dead skin began to shed, with very superficial small pustules breaking out at the ulcer sites. After taking another dose, the dead skin completely shed, and the ulcerated points healed and recovered completely.