The wife of Mr. Cen suddenly began wailing in the middle of the night, as if she did not recognize people or objects, hence they came to request a diagnosis. Upon arrival, her mournful cries resembled those of a gibbon, and despite multiple inquiries, she seemed oblivious. Mr. Cen mentioned that she had no prior illnesses, only recently complaining of mild fever and constipation. Upon careful observation, her eyes appeared dull, and when she raised her hand to gesture, her gaze did not flicker. Her lips were deeply red, with no other notable symptoms.

Considering her robust health and strong constitution, despite her prolonged crying, her breath did not weaken. The red lips indicated blood heat, the constipation suggested an excess in the stomach and intestines, and the mild fever indicated internal heat. The pathogens affecting the facial orifices caused her to not recognize people or objects. The "Treatise on Cold Damage Diseases" states, "Eyes that do not see clearly, pupils that do not respond, no exterior symptoms, difficulty in defecation, and mild fever in the body" are signs of an excess syndrome. Thus, Major Purgative Decoction was prescribed to eliminate waste, transport essence, and control the excessive qi. The prescription included:
Rhubarb Rhizoma 15g, Magnolia Bark 18g, Immature Orange Fruit 12g, Mirabilite 12g
After one dose, she recovered immediately, and the host praised the treatment.