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Yibian
 Shen Yaozi 
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titleQu Yueyun et Al. "Time-Based Treatment Differentiation and Time Prediction in the Treatise on Cold Damage Diseases"
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Gao, male, 12 years old, diagnosed on April 18, 1972. On the 10th, he began to experience aversion to cold with fever. On the 12th, he was treated, and after taking the medicine, he had profuse sweating, but the fever worsened. He no longer had aversion to cold but instead had aversion to heat, thirst, and dysphoria. In the past two days, he had fever during the day, which worsened at night, and sometimes he had delirious speech. At the time of diagnosis, his body temperature was 38.8°C, he was thirsty, sweating profusely, dysphoric, had abdominal pain that was tender to touch, had not had a bowel movement for 7 days, had scanty dark urine, a yellow and dry tongue coating, and a deep, strong pulse. This is a yangming fu-organ pattern. He was prescribed Major Purgative Decoction:
Rhubarb Rhizoma 10g, Magnolia Bark 20g, Immature Orange Fruit 10g, Mirabilite 10g
. He took the medicine at 10 a.m., experienced severe abdominal pain at 12 p.m., and passed five or six dry stools at 3 p.m., followed by foul-smelling yellow water. His body temperature dropped to 37.5°C at 5 p.m., 37°C at 7 p.m., and 37°C at 9 p.m. By 11 p.m., he was sound asleep, and the next day he was cured with no further fever. The fever subsided during the Shen, You, and Xu hours.

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