A 17-year-old male patient with a pineal gland tumor had been taking Rhubarb Rhizoma and Eupolyphaga pills for six months with little effect. He experienced daily afternoon fevers, emaciation, pale complexion, scaly skin, poor appetite, and constipation (requiring enemas for relief). His pulse was deep, thin, and faint, with a pale tongue texture and a black, moist coating in the center. Diagnosed with deficiency fatigue, he was initially prescribed two doses of Minor Bupleurum Decoction plus Sodium Sulfate, which reduced the fever, improved appetite, and softened stools. Upon follow-up, the treatment was switched to Minor Center-Fortifying Decoction with Tangshen, Astragalus Root, and Chinese Angelica, one dose daily for over 40 doses, resulting in the complete resolution of all symptoms.