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Wang Shi-xiong, styled Meng Ying, also known as Meng Yin (or Meng Ying), and Qian Zhai, with alternative names such as Ban Chi Shan Ren, Shui Xiang San Ren, Sui Xi Ju Yin Shi, and Hai Chang Ye Yun Shi (or Ye Yun Shi), originally from Yanguan, Haining, Zhejiang, later moved to Qiantang (Hangzhou). His great-grandfather, Wang Xue-quan, was skilled in medicine and authored Zhongqingtang Suibi in the year of Shi Xiong's birth, celebrating the occasion with joy. Open-minded and receptive to Western ideas, he advocated for integration, which later influenced Shi Xiong. His grandfather, Wang Guo-xiang, and father, Wang Sheng, were also practitioners of medicine. However, Shi Xiong lost his father at a young age, experiencing poverty, and by his twenties, he worked as an accountant in a salt business in Jinhua. Passionate about medicine, he spent his spare time studying medical texts, thus mastering the family's medical knowledge. Later, he resided in Dichroa County and began his medical practice in the 10th year of Daoguang (1830). Initially, he studied Jingyue Quanshu and favored warm tonics in treatment. After being admonished by his mother, Yu, Meng Ying was inspired to adopt cooling and nourishing methods, achieving remarkable success in treating warm diseases with mild yet effective prescriptions. His reputation grew, attracting countless patients and successfully treating severe cases. In the 17th year of Daoguang (1837), during a pestilence outbreak in Jiangsu and Zhejiang due to war, his beloved daughter died of cholera, prompting him to write Huoluan Lun the following year (1838). Settling in Shanghai during the Xianfeng era, he devoted himself to the study and clinical practice of warm diseases, compiling Wenre Jingwei in five volumes, with a preface dated 1852, which became a comprehensive work on warm diseases.

In 1862, he revised Suixi Ju Chongding Huoluan Lun. In 1852, he published his great-grandfather Wang Xue-quan's Zhongqingtang Suibi; in 1857, he wrote Gui Yan Lu in four volumes; in 1861, he published Suixi Ju Yinshi Pu in one volume; in 1853, he compiled Qian Zhai Jian Xiao Fang in one volume (with an appendix Qian Zhai Yi Hua); in 1854, he edited Si Ke Jian Yao Fang in four volumes, and also published Hui Kan Jing Yan Fang among others. Wang's Medical Cases, namely Hui Chun Lu and Ren Shu Zhi, were compiled chronologically from 1824 to 1857, divided into initial, continued, and third collections, with Gui Yan Lu volume four serving as the fourth compilation of medical cases. His annotated works include Nyuke Jiyao, Yan Yi Xuan Ping, Gu Jin Yi An Xuan, among others, and it is said he also authored Ji Ming Lu, Sheng Ji Fang Xuan, She Bian, Liu Zhou Yi Hua Zhu, and Yuan Ti Yi Hua Ping Zhu.

Shi Xiong spent his later years in desolation, wandering and eventually settling in Puyuan Town, Xiushui (now Jiaxing, Zhejiang), where he passed away in the 7th year of Tongzhi (1868).