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He Lian-chen (1861–1919), courtesy name Bingyuan, pseudonym Yinyan, was a native of Shaoxing, Zhejiang. His family had a long tradition of practicing medicine, and his grandfather, He Xiushan, was a renowned expert in the Shaoxing school of cold-damage disease. Influenced by his family from a young age, he also studied under the famous physician Fan Kaizhou for three years. After beginning his medical practice, he felt his knowledge was insufficient and decided to travel extensively to seek wisdom and broaden his horizons. He engaged in discussions with renowned physicians in the Jiangsu and Zhejiang regions. After the Gengzi Incident, as Western medicine spread widely in China, He Lian-chen purchased numerous translated works on Western medicine, diligently studying them to enrich his knowledge. He resided in Suzhou for a year before moving to Shanghai, where he associated closely with prominent Shanghai physicians such as Zhou Xueqiao, Cai Xiaoxiang, and Ding Fubao. He actively participated in the early organization of Chinese medicine societies in China. In the early 20th century, Zhou Xueqiao founded the *Medical Journal* and initiated the Chinese Medical Association, with He Lian-chen serving as vice president. After three years in Shanghai, he returned to his hometown, where he organized the Shaoxing Medical Association and served as its president. In 1908, together with his Shaoxing medical colleagues, he founded the *Shaoxing Medical Journal*. After 1915, he served as the评议长 (evaluation director) of the Shaoxing branch of the Shenzhou Medical Association. At that time, the Beiyang government excluded Chinese medicine from the formal education system, prompting the nationwide Chinese medicine community to rise in resistance and organize the "Medical Salvation Petition." He Lian-chen and his Shaoxing colleagues fully supported this movement.

He practiced medicine for decades, renowned for his expertise in treating seasonal diseases and his proficiency in internal medicine, pediatrics, and gynecology. His clinical practice inherited the academic thought of the Shaoxing school of cold-damage disease, and he highly regarded Yu Genchu's *Tongsu Shanghan Lun*. Building on his grandfather He Xiushan's annotations of Yu's works, he further developed the text based on his clinical experience, completing *Kanjiao Tongsu Shanghan Lun* in 1916. After its initial publication, the work was later revised and republished by scholars, gaining widespread circulation. He also revised and published other notable works, such as *Chongding Ganzheng Baojian*, *Chongding Guang Wenre Lun*, and *Zengding Cold-Damage Disease Guangyao*. He made significant contributions to the academic development of the Shaoxing school of cold-damage disease.

His other major works include *Dampness Warm Disease Seasonal Epidemic Treatment Methods*. In his later years, he compiled *Classified Cases of Nationally Renowned Physicians*, which became highly popular across the country.

He Lian-chen was deeply accomplished in medicine, passionate about Chinese medicine education, and dedicated to the preservation and organization of Chinese medical literature. He took it upon himself to preserve the national heritage and revitalize Chinese medicine.