Xue Xue (1661~1750), styled Sheng Bai, also known as Yi Piao, and by the names Huaiyun Daoren, Mojian Daoren, and Muniu Laoxiu. A native of Wu County, Jiangsu during the Qing Dynasty, he was a contemporary and equal in fame to Ye Gui. In his early years, he studied under the famous Confucian scholar Xie, excelling in poetry and prose, and was also skilled in calligraphy, painting, and martial arts. Later, due to his mother's illness with damp-heat, he devoted himself to the study of medicine, and his skills became increasingly refined. Xue Xue lived a life of boldness and simplicity, passing away at the age of ninety.

Thus, it is known that Xue Xue was not solely a medical practitioner, but he was particularly renowned for his treatment of damp-heat syndromes. His work Shire Tiaobian became a classic, making significant contributions to the field of warm diseases. He also compiled excerpts from the Neijing, resulting in the six-volume Yijing Yuanzhi (1754). Tang Da-lie's Wuyi Huijiang records eight of his Rijiang Zaji, which discuss medical theories and the use of medicine; other works such as Gaowan Dangzi (special edition manuscript), traumatology prescriptions, and Xie Yi-piao Nue Lun (manuscript) are also attributed to Xue. Xue Sheng-bai's Medical Cases and Saoye Zhuang Medical Cases were compiled by later generations.