This book is also known as Yanshi Jisheng Fang. It was written by Yan Yong-he of the Song Dynasty and completed in the first year of Baoyou (1253) of the Song Dynasty. The original book consists of ten volumes, containing 70 treatises on treatment and 400 prescriptions. In the third year of Xianchun (1267), Continuation of Prescriptions was written, which includes 24 additional medical treatises and 90 prescriptions not covered in the previous book. Both books were later lost, and the current versions are reconstructions: one is an eight-volume version Jisheng Fang compiled by Ji Xiaolan of the Qing Dynasty from the Yongle Encyclopedia, containing 56 medical treatises and over 240 prescriptions, but with significant gaps such as missing treatises, prescriptions, or ingredients, or mismatched content, published by the People's Medical Publishing House in 1956; the other is a reconstruction based on Classified Medical Prescriptions, Puji Fang, and other medical texts, referencing the Japanese edition Jisheng Fang, combining Jisheng Fang and Continuation of Prescriptions into one, containing 85 medical treatises and 520 prescriptions, more complete and closer to the original, published by the People's Medical Publishing House in 1980 under the title Revised Yanshi Jisheng Fang.

Yan compiled this book based on years of experience and clinical practice, widely collecting ancient prescriptions and proven effective formulas, organizing them under various disease categories, followed by general discussions, disease origins, pathogenesis, and main prescriptions, each prescription detailing the main symptoms, formulation, processing of materia medica, and administration methods, clearly structured and richly discussed. The book includes a wide range of prescriptions from the Han, Tang, and Song dynasties, as well as folk remedies, particularly emphasizing Hejiju Fang and Three Causes and One Disease Prescriptions, adeptly modifying commonly used ancient prescriptions, such as Kidney Qi Pill for kidney deficiency by Zhang Zhongjing, which Yan enhanced with Achyranthes Root and Plantain Seed, expanding its application to treat complex syndromes of deficiency (kidney deficiency) and excess (dampness), creating the famous Life-Relieving Kidney Qi Pill. Yan's new prescriptions emphasize balance and appropriateness, such as Returning to Spleen Decoction and Small Thistle Decoction, which are practical yet not overly aggressive, balancing strength and gentleness, and are highly regarded by later physicians.