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Ming Dynasty, Li Shi-zhen, authored. Completed in 1564 AD. This book is based on the Li family's father, Li Yanwenfour examinations invention, incorporating the essence of various theories on pulse before the Ming Dynasty, along with the author's research insights, compiled into a book. The content of the book is divided into two parts: the first part includes 27 pulses, and the latter part appends the Song Dynasty's Cui Jia-yanFour-Word Summary, which was revised and supplemented by Li Yanwen, discussing pulses in the form of four-character poetry.

This book elaborates on 27 types of pulses including floating, sinking, slow, rapid, slippery, choppy, deficient, excess, long, short, surging, faint, tight, relaxed, hollow, wiry, leathery, firm, soggy, weak, scattered, thin, hidden, moving, hurried, knotted, and intermittent. It provides detailed descriptions of the characteristics of various pulse manifestations, the differentiation of similar and different pulses, and the diseases indicated by each pulse. The descriptions of pulse manifestations often draw on the profound theories of predecessors, combined with metaphorical descriptions, followed by "body state poems" for easy memorization. Then, "similarity poems" explain the differences between the pulse and similar pulses. Finally, "disease-indicating poems" clarify the diseases indicated by the pulse. This book essentially covers the common pulses in clinical practice, with vivid and appropriate descriptions of pulse manifestations, and the diseases indicated by pulse conditions are also very relevant to clinical practice.

Because the book's theories are well-founded and its verses are rhymed and catchy, it has been widely circulated for hundreds of years, revered by later generations of medical learners, and has played a significant historical role in the development and dissemination of pulse studies. To this day, this book is still regarded as an excellent teaching material for beginners in pulse studies in the Chinese medicine community, as well as an important reference for clinical work and pulse study research.

The Four-Word Summary section takes the floating, sinking, slow, and rapid pulses from the Nan Jing as its framework, with wind, qi, cold, and heat as the main diseases, and discusses the 24 pulses from the Maijing, and the long and short pulses from the Maijue, refining the study of pulses, especially the discussions on the firm and leathery pulses, with the Four-Word Summary being the earliest. This section mainly discusses the mechanisms of pulse manifestations, pulse diagnosis methods, the normal pulses of the five zang-organs, the outline of pulse differentiation, the states of various abnormal pulses, diseases indicated by pulse conditions, the main pulses of common diseases, pulse methods for women and children, the diagnostic methods of the eight extraordinary meridians, and various "visceral exhaustion pulses" in the form of four-character verses.

Existing main versions: Ming Dynasty, Wanli 31st year, Xia Liangxin and Zhang Ding's Jiangxi reprint; Qing Dynasty, Shunzhi period print; seen in the Siku Quanshu version; Qing Dynasty, Guangxu 5th year, Saoye Shanfang print; 1956 People's Health Publishing House photolithographic edition; 1983 Henan Science and Technology Publishing House lead-print annotated edition.