A pharmaceutical work in twelve volumes, with an additional six volumes of "Materia Medica Continuation" and eight volumes of "Essential Commentary on the Preface to the Classic of Materia Medica." Written by Zou Shu during the Qing Dynasty and published in 1832. This book uses the theories of medical formulas and combinations of Chinese medicinals from texts such as the "Treatise on Cold Damage Diseases" and "Essential Prescriptions from the Golden Cabinet" to annotate and elucidate the "Shennong's Classic of Materia Medica." It thereby explains and demonstrates the therapeutic effects of the drugs recorded in the "Shennong's Classic of Materia Medica." The "Commentary and Verification" section covers 173 drugs, while the "Continuation" section covers 142 drugs, totaling 315 drugs. The "Essential Commentary on the Preface to the Classic of Materia Medica" is a compilation that annotates and explains the "preface examples" from texts like the "Shennong's Classic of Materia Medica," referencing the practical application of ancient medical formulas. Multiple Qing Dynasty editions exist, and a typeset edition was published after 1949.