This book was first published in the fourth year of the Qianlong era (1739) and is a comprehensive treatise on deficiency and detriment disease, contributing significantly to the diagnosis and treatment of deficiency syndromes in Chinese medicine. The title "Bu Ju" is derived from a passage in the "Book of Changes": "Transformation and adaptation depend on change, promotion and execution depend on flexibility, and change is ceaseless, circulating through the six voids." It signifies not adhering to a single school of thought or a biased perspective, encouraging practitioners to "adapt flexibly and treat according to the condition." Additionally, since deficiency fatigue is a condition that does not remain static?it is not confined to heat, cold, tonification, or dispersion?it requires treatment tailored to the disease, hence the title.

The book is divided into two parts, comprising fifty volumes in total. The first part focuses primarily on the treatment of internal deficiencies, with the author Wu Cheng compiling ten methods for treating deficiencies from renowned physicians throughout history as its core content. Furthermore, it discusses the treatment of the four major syndromes: cough, fever, phlegm, and blood disorders, with particular emphasis on hemorrhagic syndrome. The second part addresses external deficiencies, categorizing injuries caused by external factors such as the six climatic evils, phlegm, stagnation, food, depression, loss of blood, alcohol damage, and external parasites, which, if not healed over time, lead to deficiencies. Among these, "wind fatigue" is the most prevalent. The book is systematically organized, with each section beginning with classical principles, followed by pulse diagnosis, pathology, treatment methods, prescriptions, and case studies. The insights of previous scholars are annotated to clarify their meanings; renowned formulas and self-effective prescriptions are appended with Wu's selected discussions on formulas; and the clinical records of famous physicians or Wu's own verified cases are included to illustrate practical applications, serving as a guide for future learners.