Cold-damage disease, warm disease works, 12 volumes, Qing Dynasty Yu Gen-chu authored. The author integrated ancient and modern cold-damage disease theories and combined them with clinical experience to write. Later, it was annotated by He Xiushan, revised by He Lian-chen, supplemented by Cao Bingzhang, and organized by Xu Rongzhai, and renamed as Chongding Tongsu Shanghan Lun.

The book is divided into 12 chapters: the essence of cold-damage disease, six classical formula medicines, exterior and interior cold and heat, qi and blood deficiency and excess, cold-damage disease diagnostic methods, cold-damage disease pulse and tongue, cold-damage disease primary syndromes, cold-damage disease concurrent syndromes, cold-damage disease complicated syndromes, cold-damage disease deteriorated syndromes, cold-damage disease recurrent syndromes, and adjustment methods, detailing the treatment of cold-damage disease. Especially in cold-damage disease diagnostic methods, including observing the eyes, looking at the bite, examining the tongue, pressing the chest and abdomen, asking about thirst, inquiring about urination and defecation, checking old prescriptions, and distinguishing new and old conditions, it is quite comprehensive. The book absorbed the warm disease theories of Qing Dynasty Ye Tian-shi and others, developed the theory of externally contracted febrile sexually transmitted diseases, and was regarded as the comprehensive diagnostic and treatment book for seasonal infections in the medical community at that time.