Wei Zhi-xiu compiled, completed in the 35th year of Qianlong (1770). Originally in sixty volumes, this book was expanded and reorganized by Wang Meng-ying into thirty-six volumes. It is divided into 345 categories, collecting proven cases from famous doctors of various dynasties before the Qing Dynasty, covering all clinical departments, especially highlighting warm febrile disease. Some cases include Wang Meng-ying's annotations.

Wei himself was a clinically experienced physician with rich knowledge. Noticing that the Mingyi Lei'an from the Ming Dynasty still lacked many cases of fistula disease, and that new medical cases seen after the Ming Dynasty were quite numerous, he "miscellaneously took from recent medical books, historical biographies, geographical records, literary collections, and anecdotal records, categorizing and compiling them by sections." The entire book is divided into 345 categories, covering internal, external, gynecological, pediatric, five sense organs, and other medical conditions, with clear classification and extensive case selection, especially highlighting acute pestilence cases, with smallpox alone occupying two volumes, reflecting the severity of pestilence at the time and the compiler's dedication. His personal cases are mostly described with clarity, precise differentiation, appropriate treatment discussions, and detailed records; while for cases copied from various authors, he added interlinear notes and post-case annotations, focusing on inventing and analyzing the similarities and differences in the treatment of related cases, with relatively fair and commendable discussions.

This book currently has Siku Quanshu editions and several block-printed editions from the Tongzhi and Guangxu periods. In 1957, the People's Medical Publishing House published a photolithographic edition based on the Xinshutang reprint (1885).