This product is the mature fruit of the deciduous tree Melia azedarach (Melia azedarach L.) or Melia toosendan (Melia toosendan Sieb. et Zucc.) of the Meliaceae family. It is produced in various regions of southern China, with the best quality coming from Sichuan. The fruit is harvested when it matures in winter, impurities are removed, and it is dried. It can be used raw or stir-fried. It should be crushed before use.

bubble_chart Properties and Meridians

Bitter, cold. slightly toxic. Act on liver, stomach, small intestine and bladder channels.

bubble_chart Efficacy

Moving qi to relieve pain, killing worms to treat ringworm.

bubble_chart Indications

1. Used for various pain syndromes caused by liver depression transforming into fire. This product is bitter and cold, descending and purging, capable of clearing liver heat, draining depressed heat, and moving qi to relieve pain. It is often used together with Corydalis Tuber, adding Toosendan Fruit Powder. In addition, for hypochondriac region pain and hernia pain due to liver-stomach disharmony and liver channel heat, this product can be used, often combined with Bupleurum, Peony Root, Immature Orange Fruit, etc.
2. Used for abdominal pain due to parasitic infestation. This product can both expel parasites and relieve pain, often used together with Areca Seed, Quisqualis Fruit, etc. In addition, when this product is roasted yellow and ground into powder, it can be made into an ointment for external application to treat tinea capitis.

bubble_chart Documentation

1. Benjing: "Main warm disease cold-damage disease, great heat vexation mania, kills three worms scabies sores, benefits urination and water passage."
2. Bencao Gangmu: "Treats various hernias, worms, hemorrhoids."

bubble_chart Usage and Dosage

Decoct and take 3-10g. For external use, apply an appropriate amount by grinding into powder and mixing for application. Stir-frying reduces its cold nature.

bubble_chart Cautions and Contraindications

This product is toxic and has cumulative effects. It should not be taken in excess or for prolonged periods.

Symptoms of poisoning:

• Poisoning at regular doses: Possible side effects such as dizziness, headache, somnolence, nausea, vomiting, abdominal pain, or cutaneous pruritus, which may resolve on their own after about 10 hours.
• Acute poisoning from excessive oral intake: In adults, taking 6-8 doses at once can cause toxic hepatitis, mental disorders, visual disturbances, inflammation of the stomach and small intestine, nausea, vomiting, abdominal pain, diarrhea, internal bleeding, decreased blood pressure, respiratory and circulatory failure, and even death.

bubble_chart Modern Pharmacology

This product contains toosendanin, meliatoxins, Galanga Resurrectionlily Rhizome alcohol, and fatty oils, among others. The toosendanin in this product has a significant killing effect on Ascaris suum, earthworms, leeches, etc.; it can stimulate the smooth muscle of the intestines, increasing their tension and contractility. Chinaberry Fruit has an inhibitory effect on Staphylococcus aureus.