[Variety Source]

This product is Croton Fruit (Croton tiglum L.) mature seeds. Mainly produced in Sichuan, Guangxi, Yunnan, Guizhou and other provinces. In autumn, when the fruits are ripe and not yet cracked, they are harvested, sun-dried, the shells broken, and the seeds taken out. Use kernels or make frosting. Croton Fruit kernels are made by soaking Croton Fruit in rice water, exposing it to the sun or drying it to crack, peeling it, removing the pure kernels, stir-frying to brown; Croton Fruit cream is removing the pure Croton Fruit kernels, crushing them, Wrap with multiple layers of oil-absorbing paper, heat and bake slightly, press to remove oil, grind finely, and sieve.

[Property]

acrid, hot, extremely toxic. act on stomach, large intestine and lung channels.

[Efficacy]

drastic purgation: cold accumulation, removing swelling with water, dispelling phlegm to benifit the throat, corroding sores.

[Indications]

1. It is used for cold constipation emergencies. Croton Fruit is pungent and hot, can drastic purgation cold accumulation, and open up intestinal obstruction. Zhang Yuan-su described him as having "the ability to cut through barriers and seize doors." Suitable for those with cold food accumulation, obstruction of colon tract, constipation, abdominal distension and fullness distending pain, sudden onset of illness, and lack of qi and blood. Croton Fruit cream can be used alone in capsules, or combined with Rhubarb Rhizoma , Dried Ginger pills, such as Three-Ingredient Emergency Pill.
2. For abdominal retention of water expansion. This product has a strong drastic purgation effect to remove water and reduce swelling. To treat the above symptoms, Croton Fruit or Bitter Apricot Seed can be taken as pills. In modern times, this product is used with Jiangfan and Medicated Leaven as pills, that is, Bajiangfan pills, to treat advanced schistosomiasis, liver cirrhosis, and abdominal retention of water.
3. It is used for cold syndrome, thoracic accumulation and pharyngitis. This product can dispelling phlegm to benifit the throat to facilitate breathing. To treat congestion of phlegm and saliva, chest and diaphragm congestion, cold sweating and thoracic accumulation in the limbs, it is often used together with Fritillaria Bulb and dried stems, such as Three-Ingredient White Powder; To treat pharyngitis, when phlegm and saliva block the airway, making it difficult to breathe, or even suffocating to death, you can use Croton Fruit alone, peel it, thread it into the throat, pull it out and it will be cured; in modern times, it is used for diphtheria and laryngitis caused by laryngitis. For obstruction, blow Croton Fruit cream into the throat to cause vomiting, expel phlegm and saliva, and relieve the obstruction symptoms. In addition, if children have phlegm blockage or palpitation due to stasis due to feeding or breastfeeding, this product can be used to dispelling phlegm and eliminate phlegm. It is often used with Bile Arisaema, Cinnabar, medicated leaven is equivalent to Wan Ying Bao Chi Powder.
4. It is used for carbuncles that turn into pus but do not ulcerate and scabies malignant sores. This product can be used externally to corrode flesh and treat sores. To treat carbuncle that is swollen into pus but not ulcerated, it is often treated with frankincense, myrrh, cochinchina momordica seed, castor bean can be used together with external application to the affected area to corrode the skin and promote ulceration of expelling pus; to treat malignant sores, use this product alone to fry oil, mix Realgar with oil, calomel At the end, apply it externally on the sore surface.

[Documentation]

1. Benjing: "Broken stuffiness, abdominal mass, firm accumulation, persistent fluid retention, phlegm habit, large abdominal retention of water, swelling, cleaning five zang-organs six fu-organs, opening obstruction "Croton Fruit is endowed with a masculine and vigorous nature, and it has the ability to cut through obstacles and seize doors. The qi and blood are not weak, and the evil spirits are strong." Croton Fruit and Rhubarb Rhizoma are both anti-purgation agents, but Rhubarb Rhizoma frigidity is suitable for those with multiple internal diseases and heat; Croton Fruit is hot in nature. It is suitable for those with internal diseases caused by cold. Therefore, when Zhongjing treats diseases caused by cold and aversion to heat, he usually uses Rhubarb Rhizoma. When Dongyuan treats diseases caused by internal organs, he usually uses Croton Fruit."

[Usage and Dosage]

Take it as a pill and take it as powder, 0.1 to 0.3g each time. Most of them are made into Croton Fruit cream and used. Appropriate amount for external use.

[Precaution]

It should not be used by pregnant women and the infirm. Fear of lobedleaf pharbitis seed.

[Processing and Storage]

Before use, the heart and membrane must be removed. If the membrane is not removed, it will hurt the stomach, and if the heart is not removed, it will cause nausea. Raw Croton Fruit is very toxic and can cause foaming when applied externally. The Croton Fruit oil contained in it will react with the alkaline intestinal fluid in the intestines to precipitate Croton Fruit oleic acid, causing severe diarrhea and enteritis. In order to reduce the toxicity and reduce its side effect, it needs to be crystallized or powdered into medicine.

Croton Fruit frosting method: Crush the clean Croton Fruit kernels, wrap them in multiple layers of oil-absorbing paper, heat and bake slightly, press to remove most of the oil, grind finely, and sift. Croton Fruit kernels contain 53~57% of Croton Fruit oil. After being made into cream, it is required to contain about 10% of Croton Fruit oil. The toxicity of Croton Fruit cream has been reduced but it is still a highly toxic drug and must be used with caution.

[Modern Pharmacology]

This product contains Croton Fruit oil, 34% ~ 57%, which is combined with Croton Fruit oleic acid and glycerol. The oil also contains Croton Fruit diethyl alcohol and various Croton Fruit triglycerides. In addition, it also contains Croton Fruit toxins, Croton Fruit glycosides, alkaloids, β-sitosterol, etc. Croton Fruit oil is used externally and has a strong irritating effect on the skin. Taking half a drop to 1 drop orally can cause a burning sensation and vomiting of the mucous membrane in the mouth and stomach, and may cause multiple large amounts of watery diarrhea in a short period of time, accompanied by severe abdominal pain and tenesmus; Croton Fruit decoction is effective against Staphylococcus aureus and diphtheria bacillus, influenzae, and Pseudomonas aeruginosa all have varying degrees of inhibitory effects; Croton Fruit extract has significant inhibitory effects on mouse fleshy tumor 180, Ehrlich abdominal cancer, etc.; Croton Fruit oil, Croton Fruit resin, and Croton Fruit Fruit alcohol lipids have weak carcinogenic activity.