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Yibian
 Shen Yaozi 
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formula nameLonicera and Forsythia Powder
sourceVolume 1 of Wenbing Tiaobian
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bubble_chart Composition

Forsythia 30 gm, Honeysuckle 30 gm, Platycodon Root 18 gm, Peppermint 18 gm, Bamboo Leaves 12 gm, Raw Licorice Root 15 gm, Schizonepeta 12 gm, Fermented Soybean 15 gm, Arctium Seed 18 gm.

bubble_chart Preparation and Dosage

Grind into powder. Take 18 grams each time, decoct with fresh reed root soup until the aroma is strong, then take immediately without overcooking. Lung medicine should be light and clear; overcooking will make it thick and enter the middle burner. For severe cases, administer every two hours, three times a day, and once at night; for mild cases, administer every three hours, twice a day, and once at night. If the illness does not resolve, repeat the dose.

bubble_chart Efficacy

Releasing exterior with pungent-cool, clearing heat and removing toxin.

bubble_chart Indications

At the onset of warm disease, fever without sweating, or sweating is not smooth, slight aversion to cold, headache, thirst, cough, sore throat, red tongue tip, thin white or thin yellow coating, floating and rapid pulse. Currently used for acute upper respiratory tract infections.

bubble_chart Formula Principles

In the formula, Lonicera and Forsythia, with their pungent and cool properties, lightly disperse and expel pathogens, clearing heat and removing toxins, serving as the sovereign herbs. Mentha and Great Burdock Achene, also pungent and cool, disperse wind and clear heat, while fineleaf nepeta spike and Fermented Soybean, with their pungent dispersing nature, expel pathogens through the exterior and release the flesh, acting as the minister herbs. Platycodon Root and Liquorice Root clear heat, remove toxins, and benefit the throat, serving as the assistant herbs. Bamboo Leaf and Reed Rhizome resolve depression, discharge heat, promote fluid production, and quench thirst, acting as the envoy herbs. Together, these herbs synergistically achieve the effects of pungent and cool releasing of the flesh, dispersing wind-heat, relieving irritability, and benefiting the throat.

bubble_chart Modern Pharmacology

Pharmacological Effects of Lonicera and Forsythia Powder Journal of Traditional Chinese Medicine 1986(3):59,

  1. Antipyretic: In experimental hyperthermia in rats, administration of Lonicera and Forsythia Powder in both sachet and tablet forms resulted in a reduction of body temperature, with the sachet form showing a more pronounced effect.
  2. Anti-inflammatory: The sachet form of Lonicera and Forsythia Powder demonstrated significant anti-inflammatory effects against various causes of inflammation, whereas the tablet and decoction forms showed weak or no effect on certain inflammations.
  3. Anti-allergic: It significantly inhibited passive cutaneous anaphylaxis and immediate hypersensitivity reactions induced by Snakegourd Root in both rats and mice, and reduced the mortality rate from anaphylactic shock.
  4. Immune-enhancing: Without increasing the weight of immune organs, the sachet form significantly enhanced the phagocytic ability of peritoneal macrophages in mice.
These effects undoubtedly provide an important pharmacological basis for the clinical application of Lonicera and Forsythia Powder in the treatment of external-contraction febrile disease.

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