drug name | Densefruit Pittany Root-bark |
alias | Densefruit Pittany Root-bark |
[Variety Source]
This product is the root bark of Dictamnus dasycarpus (Dictamnus dasycarpus Turcz.), a perennial herbaceous plant of the beautiful steetgum resin family. Produced in Liaoning, Hebei, Sichuan, Jiangsu and other places, it is excavated in spring and autumn, removes the fibrous roots and outer bark, cuts it lengthwise, removes the core of the wood, slices it, and dries it in the sun.
[Property]
bitter, cold. act on spleen and stomach channels.
[Efficacy]
clearing heat and drying dampness, removing toxin.
[Indications]
- For dampness-heat sores, eczema and scabies. This product clears heat and removes dampness, clears heat and removes toxin, dispels wind and relieves itching. Used to treat dampness-heat sores, skin ulcers and yellow water dripping, often used with Atractylodes Rhizome, Sophora, Lonicera drying Use the same product as dampness removing toxin. It is used to treat eczema, scabies and itchy skin. It is often used with Sophora, Saposhnikovia Root and belvedere fruit. It can be taken internally or externally. .
- It is used for jaundice with red urine and dampness-heat arthralgia. This product not only clears heat and drying dampness, but also dispels wind and relieves arthralgia. To treat dampness-heat jaundice, red urine, use Virgate Wormwood, which has the effect of promoting gallbladder and reducing jaundice. To treat wind-dampness heat arthralgia, joint redness, swelling, heat and pain, use Atractylodes Rhizome, Phelloendron Bark and Achyranthes Root together play the role of clearing heat and drying dampness, dispelling wind and relieving paralysis.
[Documentation]
- Benjing: "Mainly head wind, jaundice, cough, stranguria: swelling and pain in the vagina of women, fixed arthralgia, dead muscles, unable to bend, stretch, stand or walk."
- Yaoxing Lun: "Cures all heat toxin wind, aversion to wind, wind sores, scabies, red rot...mainly relieves heat yellow, wine yellow, acute jaundice, grain yellow, labor yellow, etc."
[Usage and Dosage]
Decoct and take, 6~10g. Appropriate amount for external use.
[Precaution]
Use with caution in patients with flat cold.
[Modern Pharmacology]
This product contains ascorbic acid, ascorbic acid lactone, sitosterol, choline, zenpione, etc.
- Antibacterial effect: In vitro tests, the 1:4 water infusion has varying degrees of inhibition against a variety of pathogenic fungi, such as Trichophyton violaris, Trichophyton concentricum, and Flavophyton xanthophyton. However, it has been reported that the ether, ethanol and water extracts of this product have no effect on Isococcus aureus, large intestine bacilli Pseudomonas aeruginosa and Mycobacterium phlei. 1:20 decoction has no killing effect on vaginal Trichomonas.
- Effects on the heart blood duct system and blood: The leukophylline contained in this product has an exciting effect on the isolated frog heart in small amounts, which can increase myocardial tension, minute output and stroke volume. It has obvious contraction effect on isolated rabbit ear blood vessels. The Pricklyash Peel base contained has an antiarrhythmic effect, and the mycoconidine has an Ephedra base-like effect, which can increase the blood pressure of anesthetized cats, enhance the cat's instantaneous membrane contraction, dilate the coronary arteries, and enhance the pressor effect of epinephrine.
- Effects on uterus and intestinal smooth muscle: Leucine has a strong contractile effect on the uterus smooth muscle of rabbits and guinea pigs. Indipine can also strengthen the contraction of uterus in cats or rabbits and strengthen the effect of epinephrine on uterus. Leucine and capsaicin have no effect on the spontaneous contraction of rat uterus, but they can weaken the contraction of rat uterus caused by oxytocin, while aphromonine can enhance it. Indine can inhibit the contraction of small intestine, and epitamine can inhibit the spasm of isolated rabbit ileum caused by barium chloride. Indine and aperitine can also relax the sphincter of Oddi. Reports indicate that alpinine and apermine can relax the sphincter of Oddi. The mixture of alkaloids, alkaloids, etc. has a stronger antispasmodic effect on rats and guinea pigs than a single alkaloid.
- Anti-cancer effect: The results of eosin staining method show that the non-polar solvent extract and volatile oil of this product have in vitro anti-cancer activity. From the ether extract of this product, sempinone, alkaloids and alkaloids derived from the volatile oil were isolated. A colorless transparent liquid is its active anti-cancer ingredient in vitro. Its 45% concentration can kill Ehrlich carcinoma, S180 and U14 cells, while Phelloendron Bark ketone, limonin and β-sitosterol are ineffective. .
- The root bark of Dictamnus albus L. has an antipyretic effect. Giving its decoction orally to rabbits with fever (warm acupuncture method) can reduce body warm purgation. Intravenous injection of another densefruit pittany root-bark D. Albus var.Caucasicus extract into dogs can shorten the blood clotting time.
- Other effects: The mixture of alkaloids, indipine and capepine can reduce the effect of epinephrine on the seminal vesicles of guinea pigs. Indiamine can paralyze muscles and cause a progressive decrease in blood pressure in mammals due to involvement of the myocardium. . Fenugreek seed base can increase the tension of striated muscles and enhance the excitability of spinal cord reflexes. The pharmacological activity of common fenugreek seed base is weak, but in early years it was reported that it can reduce the time value of nerves in neuromuscular specimens, and the time value of muscles first decreases and then increases. , In addition, common fenugreek seed alkali has certain anti-cancer effects, and 12.5mg/kg can extend the life of P388 leukemia mice by 31%.
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