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Yibian
 Shen Yaozi 
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drug namePokeberry Root
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[Variety Source]

This product is the dried root of Pokeberry Root (Plytolacca acinosa Roxb.) or vertical Pokeberry Root (Phytolacca americana L.) of the Pokeberry Root family. Excavate from autumn to next spring, remove fibrous roots and sediment, cut into pieces or slices, and dry in the sun or shade. Hard quality. The smell is slight, the taste is slightly sweet, and the tongue is numb after chewing for a long time.

[Property]

bitter, cold; toxic. act on lung, spleen, kidney and large intestine channels.

[Efficacy]

Dispel water and reduce swelling, relieve constipation, remove toxin and dissipate stagnation.

[Indications]

It is used for edema swelling and inability to defecate; for external treatment of carbuncles and sores.

[Documentation]

  1. Benjing: "Lord Shuizhang, hernia, paralysis; ironing out carbuncles and swelling, killing ghosts and spirits."
  2. Bielu: "Cure pathogenic qi, edema, wilting impediment, abdominal distension and fullness in the chest, dredge five zang-organs, and disperse water qi."
  3. Yaoxing Lun: "Can relieve ten kinds of diarrhea Water disease. Pharyngitis is blocked, thin slices are boiled, and the throat is swollen and the outer part is thin. "
  4. "The white one has good garlic." Quoted from Gangmu )
  5. "materia medica 元明蒞": "Water vapor edema is the same as foxtail millet rice cooked with porridge."
  6. Bencao Tongxuan: " For pediatric acne, use Fistular Onion Stalk to fill the navel."

[Usage and Dosage]

3~9g; for external use, mash the fresh product or dry it into powder and apply it.

[Precaution]

Not recommended for pregnant women.

[Processing and Storage]

Store in a dry place to prevent mildew and moth.

[Modern Pharmacology]

The root contains Pokeberry Root glycosides A, B, C, and D.

  1. Effects on immune function: Pokeberry Root polysaccharide (PI) 50mg/kg can be administered to mice, which can promote the phagocytosis of peritoneal macrophages, stimulate the proliferation of mouse spleen lymphocytes and induce the production of splenocytes. Ishi. PI can also induce the production of interleukin 1 (IL-1) in mouse peritoneal macrophages.
  2. Anti-inflammatory effect.
  3. Antibacterial and antiviral effects: Pokeberry Root decoction and tincture have certain inhibitory effects on influenza bacilli, pneumoniae and Neisseria in vitro, and decoction has a better effect than tincture.
  4. Anti-tumor effect.
  5. Effects on the respiratory system: Partial infusion of Pokeberry Root alkaloids has a significant antitussive effect on mice challenged with ammonia mist;
  6. Effects on the kidneys: Pokeberry Root extract infused into toad kidneys can significantly increase urine output , dripping directly onto the kidneys or webs can dilate capillaries and increase blood flow. Its function may be the result of dilating glomerular capillaries and accelerating renal blood circulation. Its potassium salt may play a certain additional role.
  7. Effects on the digestive system: mice fed PS-E 50mg/kg have a significant inhibitory effect on intestinal carbon dioxide advancement, 100mg/kg has a significant inhibitory effect on stress-induced ulcer, but 200mg/kg can induce Or aggravate gastric ulcer.
  8. Effects on metabolism: Pokeberry Root total saponins administered to mice can significantly increase the incorporation of tritium-labeled thymidine 3H-TdR into DNA. The experimental results indicate that Pokeberry Root total saponins may be an organism that activates nucleoside reductase. Active substances.
  9. Other effects: The resin-like substance in the vertical Pokeberry Root root has a strong inhibitory effect on the central nervous system. 50mg/kg can cause the death of cats. Its liquid extract can cause cats to vomit strongly. 1ml can inhibit the cat’s breathing and circulation. , 4ml can cause heartbeat and respiratory arrest.

[Modern Application]

  1. Treatment of chronic tracheitis.
  2. Treat psoriasis.
  3. Treat breast hyperplasia.

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