bubble_chart Overview

Craniosynostosis refers to the premature fusion of cranial sutures in infants and young children, which restricts skull expansion, leading to skull deformation and brain dysfunction. It is also known as premature cranial suture closure or cranial suture ossification. The main clinical manifestations include skull deformation, increased intracranial pressure, intellectual developmental disorders, and ocular symptoms. The incidence of this condition shows no regional or gender differences. The primary treatment involves cranial suture reconstruction surgery. The prognosis is generally favorable, with better surgical outcomes if performed within the first six months after birth, while delayed surgery results in poorer outcomes.

bubble_chart Clinical Manifestations

1. Skull deformities such as scaphocephaly, plagiocephaly, brachycephaly or flat head, and oxycephaly.
2. Increased intracranial pressure manifestations: The child may experience dysphoria, restlessness, vomiting, etc., and may present with bilateral optic disc edema.
3. Intellectual developmental disorders: Low intelligence, slow response.
4. Ocular symptoms: Protrusion of the eyeballs, limited movement, lateral displacement, resulting in dissociated strabismus.

bubble_chart Diagnosis

1. The infant presented with cranial deformation accompanied by increased intracranial pressure, intellectual developmental disorder, and dissociated strabismus after birth.
2. Skull X-ray images showed indistinct cranial sutures, increased bone density at the corresponding suture sites, and more pronounced convolutional markings.

bubble_chart Treatment Measures

1. Artificial cranial suture reconstruction surgery during brain development, with better outcomes if performed within 6 months after birth.
2. Preventive infection control, neurotrophic therapy, symptomatic treatment, etc.

The occurrence of this disease may be related to certain developmental defects in the fetal mesoderm, the consequence of which affects the expansion of the cranial cavity and the growth and development of the brain. Therefore, once an infant is found to have cranial deformity after birth, a specialist should be consulted to strive for early diagnosis and surgery during the brain development period for better recovery. Postoperative periodic skull X-ray follow-ups are necessary to monitor the re-closure of ununited skull (hydrocephalus) sutures. If re-closure occurs, repeat surgery is required.

bubble_chart Cure Criteria

1. Cure: Symptoms of increased intracranial pressure disappear, exophthalmos and eye movement improve, and neurological function recovers.
2. Improvement: Symptoms of increased intracranial pressure are alleviated, and neurological symptoms stabilize.
3. No cure: Symptoms of increased intracranial pressure and neurological damage show no improvement.