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Yibian
 Shen Yaozi 
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formulaPlague-Clear Toxin-Vanquishing Decoction
sourceYizhen Yide
smart_toy
bubble_chart Preparation and Dosage

Gypsum (Gypsum Fibrosum) 50gm (a large dose is 6 to 8 liǎng, a medium dose is 2 to 4 liǎng, and a small dose is 8 qián to 1.2 liǎng.)
Small Unprocessed Rehmannia Root (Radix Rehmanniae Recens) 15gm (large dose 6 qián~1 liǎng, medium dose 3 qián~5 qián, small dose 2~4 qián)
Rhinoceros Horn 5gm (a large dose is 6 to 8 qián, a medium dose is 3 to 4 qián, and a small dose is 2 to 4 qián.)
Makawaren (Rhizoma Coptidis) 6gm (a large dose is 6 to 4 qián, a medium dose is 2 to 4 qián, and a small dose is 1 to 1.5 qián.)
Gardenia (Fructus Gardeniae) 10gm
Platycodon Root (Radix Platycodonis) 10gm
Skullcap Root (Radix Scutellariae) 10gm
Anemarrhena (Rhizoma Anemarrhenae) 10gm
Red Peony Root (Radix Paeoniae Rubra) 10gm
Scrophularia Root (Radix Scrophulariae) 15gm
Forsythia (Fructus Forsythiae) 10gm
Bamboo Leaf (Herba Lophatheri) 10gm
Peony Bark (Cortex Moutan Radicis) 10gm
Liquorice Root (Radix Glycyrrhizae) 5gm

After decocting gypsum for more than ten minutes, add the remaining herbs and continue decocting. Rhinoceros horn can be ground into juice for consumption, or powdered, or decocted first and then mixed in, to be taken in two doses. At the onset of an epidemic disease, symptoms such as aversion to cold with fever, splitting headache, dysphoria and delirium, hot body with cold limbs, tongue pricks and parched lips, vomiting and diarrhea, and six pulse conditions—deep, thin, and rapid pulses require a large dose; deep and rapid pulses require a medium dose; floating, large, and rapid pulses require a small dose.

bubble_chart Efficacy

Clearing heat and purging fire, cooling blood to remove toxin.

bubble_chart Indications

Dampness-heat epidemic toxin and all types of fiery heat syndromes. Blazing of both qi and blood, high fever and mania, restlessness and insomnia, or unconsciousness and delirious speech, splitting headache, extreme thirst and desire to drink, sore throat and retching, skin rashes and hematemesis, crimson tongue and parched lips, deep and thin rapid pulse, or deep and rapid pulse, or floating, large, and rapid pulse.

bubble_chart Formula Principles

This formula is derived from the modifications of three formulas: White Tiger Decoction from the "Treatise on Cold Damage Diseases," Peony Root Rehmannia Decoction from the "Waitai Miyao" citing the "Xiaopin Fang," and Coptis Detoxification Decoction from the "Waitai Miyao" citing the "Cui's Formula." The formula heavily uses Gypsum combined with Anemarrhena and Liquorice Root to clear the heat of the Yangming; Coptis Rhizome, Skullcap Root, and Gardenia are used together to purge the excess fire of the triple energizer; Rhinoceros Horn, Moutan Bark, Unprocessed Rehmannia Root, and Red Peony Root specifically cool the blood to remove toxins and resolve stasis; Forsythia, Scrophularia Root, Platycodon Root, and Liquorice Root clear heat and expel pathogenic factors, benefiting the throat; Bamboo Leaf clears the heart and promotes urination, guiding heat downward. The combination of these herbs not only clears the fire of the qi aspect but also cools the heat of the blood aspect, making it a primary formula for treating the blazing of both qi and blood.

bubble_chart Pattern Identification

If spots appear, add Dyers Woad leaves and a small amount of Cimicifuga Rhizome, 1.2-1.5 grams; for constipation, add raw rhubarb; for extreme thirst, add Gypsum and smallpox powder; for chest and diaphragm depression, add Sichuan Coptis, Submature Bitter Orange, Platycodon Root, and Trichosanthis Fruit frost.

bubble_chart Modern Application

Currently used for epidemic encephalitis B, epidemic cerebrospinal meningitis, sepsis, and other conditions presenting with symptoms of blazing of both qi and blood.

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