bubble_chart Efficacy

Relieving both the exterior and interior, clearing heat, and stopping diarrhea.

bubble_chart Indications

The external contraction exterior pattern has not resolved, pathogenic heat has entered the interior, there is body heat, foul-smelling diarrhea, a burning sensation in the anus, epigastric stuffiness, heat and vexation in the chest and epigastrium, panting with sweating, dry mouth and thirst, a yellow tongue coating, and a rapid pulse.

bubble_chart Formula Principles

The formula heavily utilizes Pueraria Root, which not only releases the exterior to expel pathogenic factors on the surface but also lifts clear yang, stops diarrhea, and harmonizes the interior. Since the interior heat is intense, Skullcap Root and Coptis Rhizome are used to clear the interior heat, while Liquorice Root harmonizes the actions of the other herbs. Together, they achieve the dual effects of resolving both the exterior and interior, clearing heat, and stopping diarrhea.

bubble_chart Pattern Identification

1. Fever with diarrhea.
2. Burning sensation in the anus.
3. Red tongue with yellow coating.
4. Rapid pulse.

bubble_chart Formula Modification

1. For those with headache: add Dahurian Angelica and Sichuan Lovage Rhizome.
2. For severe heat: add Lonicera.
3. For food stagnation: add Germinated Barley, radish seed, and hawthorn fruit.
4. For vomiting: add Pineilia and Bamboo Shavings.
5. For abdominal pain: add Aucklandia Root and Peony Root.
6. For acute bacterial dysentery: add chinese pulsatilla root, Aucklandia Root, and ash bark.
7. For enterovirus: add Lonicera, Isatis Root, Peony Root, and Purslane Herb.

bubble_chart Documentation

1. Antiarrhythmic effect "Jilin Chinese Medicine" 1986(6):30. The water-alcohol precipitate of this formula can counteract arrhythmias induced by Aconite Mother Root alkaloid in rats, arrhythmias caused by chloroform-adrenaline in rabbits, arrhythmias induced by calcium chloride in rats, and arrhythmias triggered by chloroform in mice. Experiments also show that the water-alcohol precipitate of this formula has a significant slowing effect on the normal heart rate of experimental animals, possibly because it antagonizes the heart rate-accelerating effect of isoproterenol.
2. Antibacterial and antipyretic effects "Chinese Patent Drug Research" 1986(12):39. This formula has a significant antipyretic effect on rabbits with fever induced by the pentavalent vaccine. At the same time, it exhibits certain antibacterial effects against Staphylococcus aureus, Diplococcus pneumoniae, and dysentery bacilli both in vitro and in vivo.

bubble_chart Cautions and Contraindications

Cold-dampness dysentery or deficiency-cold of spleen and stomach diarrhea should be avoided.

bubble_chart Modern Application

Acute gastroenteritis, bacterial dysentery, conjunctivitis, dacryoadenitis, stomatitis, rosacea, hypertension, gastrointestinal common cold.