A native of Chongchuan (now Nantong City, Jiangsu Province), he was often sick in his childhood. He began to study spiritual medicine as a teenager and specialized in surgery for more than 40 years. He wrote 12 volumes of Waike Zhengzong (1617), collecting surgical prescriptions since the Tang Dynasty and combining them with Written from my own clinical experience.

Chen has noble medical ethics and attaches great importance to the construction of medical ethics. The "Five Precepts and Ten Essentials for Physicians" he wrote set forth strict requirements for doctors and formulated a comprehensive system of medical ethics, such as not caring about consultation fees, treating rich and poor patients equally, diligently studying medical skills, and selecting drugs, etc., which are still of great significance today.