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Jinyuan Sidajia refers to Liu Wan-su (Hejian), Zhang Cong-zheng ( >Zihe), Li Gao (Dongyuan), Zhu Zhen-heng (Danxi)Four famous medical scientists.

Chinese medicine has a long history. During the Song, Jin, and Yuan dynasties, there was a vigorous debate among various schools of thought. The four major schools were outstanding representatives at that time. The academic thoughts of the four major schools each have their own characteristics. They wrote books, established their own schools, and discussed enthusiastically. From this, the Hejian School, the Gongxie School, the Yishui School, and DanxiSchool of thought and other four major schools.

Liu Wan-su is a representative figure of the Hejian School. The central topic of this school's research is the pathogenesis and syndrome differentiation treatment of fire Rebing syndrome, and they advocate the theory that "six qi are all from cremation". Zhang Zi-he inherited and developed the academic thoughts of Liu Wan-su. He is a representative figure of the school of attacking evil, emphasizing that "diseases arise from evil, and attacking evil causes the disease" , "We have accumulated rich experience in the clinical application of the three methods of sweating, vomiting and lowering. The founder of Yishui School is Zhang Yuan-su, and the research topic is mainly zang-fuorgan pathogenesis and syndrome differentiation treatment, and formed a complete set of zang-fuorgan syndrome differentiation theory system. His disciple Li Gao inherited and expanded it. Zhu Dan-xi is a representative of the Danxi school of internal injury to the spleen and stomach. The idea of ​​the School of Attacking Evil advocates "Yang is always in excess and Yin is often deficient" and the "Fire Theory". The treatment focuses on nourishing Yin and reducing fire, creating a new situation in the treatment of internal injuries Zabing.

The academic thoughts and arguments of the four great masters had a profound impact on the development of medicine in later generations. They not only promoted the theory of pathogenesis and the theory of evil and righteousness in Chinese medicine, but also promoted zang-fu organ syndrome. It laid the foundation for the formation of the theory of warm diseases in the Ming and Qing dynasties, and also promoted the development of clinical medicine. Since the Four Great Masters, the development of Chinese medicine has been like a hundred boats competing against each other, changing with each passing day. To this day, the academic thoughts of the four masters, and even their specific treatment principles and prescriptions, are still widely used in clinical Chinese medicine.