He lived approximately between 1030 and 1100. According to the cold-damage disease Wei Zhi Lun case records, Han once practiced medicine in "Xing and Ci counties" (now Xingtai and Cixian in Hebei), "Huai and Wei counties" (now Bi County and Ji County in Henan), and "Fuyang" (in present-day Hebei). It can be inferred that Han's ancestral home was in the border area between present-day Hebei and Henan provinces.

Han had profound research on external-contraction febrile diseases. He studied Zhongjing's cold-damage disease theory for over 30 years and completed the cold-damage disease Wei Zhi Lun in 1085, a two-volume work of over 20,000 words, which promoted Zhongjing's ideas and was rich in innovative spirit. Han advocated the use of pungent-cool herbs to relieve the exterior, and his formulas often included Bupleurum, Mint, Gypsum, Anemarrhena, and other pungent-cool clearing and resolving ingredients. This not only had the effect of correcting biases and saving from harm at a time when doctors commonly used warm herbs to treat external contraction diseases, but also played a significant foundational role in the formation of warm diseases in later generations.