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A native of Qishui (now Xishui County, Hubei Province), he was born into a family of world-class doctors. He was smart and eager to learn since he was a child, and he never forgot what he read. He studied the pulse books of Huangdi and Bian Que, and soon he understood their theories and was able to elucidate new meanings. He was dissatisfied at that time. 20. Later, An was diagnosed with seasonal disease deafness, and further studied medical books such as Lingshu, Taisu, Jiayi Jing), and found out that hundreds of schools of thought were related to medicine. Explore and understand.

Pang An-shi He has superb medical skills and can respond to patients' urgent needs. He practices medicine without seeking personal gain. He often allows patients to stay in his own home and take care of them personally until they are cured and sent away.

In his later years, he referred to the theories of various schools and combined with his personal experience to write 6 volumes of Shanghan Zongbing Lun, which supplemented and developed the thoughts of Zhongjing. Its outstanding feature is that it focuses on elucidating warm febrile disease and advocates distinguishing warm disease from disease caused by cold, which is a great development for the science of external contraction diseases.

Ponzi admired Nan Jing very much and wrote tens of thousands of words about Nan Jing, but it is a pity that it has not been handed down to the world. He also wrote Main Duplicate and Supplement to materia medica, both of which have been lost.