This book was written by the renowned late Qing and early Republic period physician who integrated Chinese and Western medicine, Zhang Xi-chun. It has been widely circulated and has had a significant impact. The book consists of seven issues and thirty volumes, presented in a periodical format. The content is divided into five parts: medical prescriptions, medicinal substances, medical theories, medical anecdotes, and medical case studies. It specifically reflects his exploration in integrating Chinese and Western medicine, primarily focusing on Chinese medicine while incorporating the strengths of Western medicine to elucidate Chinese medical theories, enrich treatment methods, and promote the academic thought of Chinese medicine. Throughout his life, he engaged in clinical practice of Chinese medicine, adopting modern experimental scientific methods, and devoted himself to the integration of Chinese and Western medicine, pioneering a new academic trend in China.

The section on prescription science includes a total of 173 formulas. Each formula is accompanied by explanations of its indications, the theoretical basis for the combination of medicinals, modifications, and administration methods. Some formulas are also analyzed using Western medical theories, offering high clinical practical value.