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Wu You-xing wrote pestilence fall in the fifteenth year of Chongsuo (1642). According to Sikuquanshu General Catalog, Wenyi Lun 2 Volume, with 1 additional volume, the main versions include the early Qing Dynasty engraving, Sikuquanshu, etc. During the Kangxi period, there were already engraved editions in Japan, and there were also many domestically explanatory books. In the 49th year of Qianlong's reign (1784), Wan Cuitang and others wrote supplementary annotations Wenyi Lun , and Tongzhi 3 In 1864, Fan Chuan Wenchengtang and others published the original version as Wenyi Lun with supplementary notes. After the founding of the People's Republic of China, there were many types of printed versions and commentaries.

The first volume contains 50 papers, explaining the cause, pathogenesis, syndromes and treatment of pestilence, and discussing the differences between pestilence and disease caused by cold from many aspects. The second volume contains 36 articles, focusing on the concurrent symptoms of pestilence. Several articles discuss the name and reality of pestilence and the syndrome and treatment of pestilence. "Supplement" is a volume in which the author has added chapters such as "correction of names" and "corrections of "disease caused by cold cases"", which will provide a lot of enlightenment to readers.

Wu believes that the cause of pestilence is invisible "violent energy" that invades the human body through the mouth and nose. There are many types of violent energy, each with its own "specific" or "neutral" nature, that is, different violent energy has the specificity of invading certain organs, and people or animals also have different sensitivities to certain violent energy. He proposed the principle of "knowing how to use substances to control qi, and only one medicine can cure a disease." The intrusion pathways of hostility can be divided into "from the heaven" (air pestilence) and "pestilence" (contact pestilence). It can form either an epidemic epidemic or a sporadic epidemic. Proposed treatment methods such as "Da Yuan" and "Three Eliminations".

As for the parts of the human body where epidemic evil invades, the book believes that it is mainly in the "membrane source" (a part of the human body that is "half-exterior and half-internal") where the evil lurks inside and is difficult to penetrate, and can cause external and internal spread. In nine cases, treatment methods should be established for transmission syndrome and concurrent syndrome and different conditions. Wu's own recipes such as Membrane-Source-Opening Decoction and Juban Decoction have strong clinical practical value. Among them, Membrane-Source-Opening Decoction is mainly used to treat pestilence at the beginning, first aversion to cold, then fever, then fever without chills, day and night fever, worse in the afternoon (from afternoon to evening), headache, body pain and other symptoms. This prescription has the effects of opening up the membrane source, removing filth and turning turbidity, and reducing fever. Wu's treatment of epidemics attaches great importance to the application of treatment methods. He pointed out that there are more than 30 types of symptoms of pestilence. In the treatment of diseases, he especially attaches great importance to the use of Rhubarb Rhizoma "to expel evil and remove poison".

Wu's pioneering work on the causes and transmission pathways of exogenous pestilence was the first to treat pestilence in my country and had a great influence on later generations such as Dai Tian-zhang. In the Qing Dynasty, warm disease experts such as Ye Tian-shi, Xue Sheng-bai, Wu Ju-tong, and Wang Meng-ying did not continue to explore according to Wu's ideas, but returned to the traditional thinking method of Chinese medicine, which gave rise to Wu's theory of hostility. failed to be fully developed.

Wenyi Lun There are dozens of printed editions from the early Qing and Kangxi years, other Qing editions, Japanese editions, and the "Chinese Medical Complete Works" edition. There are also several collated and typeset editions after the founding of the People's Republic of China.